Hydrolyzed Versus Nonhydrolyzed Protein Diet in Short Bowel Syndrome in Children

Abstract

Intestinal permeability, energy, and nitrogen balance in short bowel syndrome were not influenced in the short term by hydrolysis of the enteral nitrogen source.

Interdisciplinary management of infantile short bowel syndrome: resource consumption, growth, and nutrition

“…Duration of ETN did not differ between 5 patients who received polymeric nutrition (of whom 4 breast milk) and the 4 who received semielemental nutrition. Likewise Ksiazyk et al [46] did not find any difference in absorption between polymeric and semielemental nutrition. Moreover, Koehler et al [22] also did not find an association between the type of formula used and successful weaning from ETN.…”

Glutamine and Whey Protein Improve Intestinal Permeability and Morphology in Patients with Crohn’s Disease: A Randomized Controlled Trial

“…There are a few reports on whey protein or its constituents on IP [48,49] and intestinal mucosa [50,51]; however, the conclusions were unyielding. It is conceivable that a high protein diet might have played a role, as in both the GG and ACG protein intake increased by nearly 40%, to the target of 1.5 g/kg/day.…”

Hospital Based Nutrition Support: A Review of the Latest Evidence

“…The studies comparing these formulations in patients at risk for malabsorption have failed to show any benefit with elemental formulations despite theoretical benefits [41][42][43]. Even in patients with documented short bowel syndrome the data is conflicting if there is any benefit [44][45][46]. Similarly, in patients with active Crohn's disease, outside of one study which showed improved remission rates with elemental formulations, no other studies have found a benefit for elemental over nonelemental formulations [47].…”