The evolution of compact density heat gadgets demands effective thermal transportation. The notion of nanofluid plays active role for this requirements. A comparative account for Maxwell nanofluids and Williamson nanofluid is analyzed. The bioconvection of self motive microorganisms, non Fourier heat flux and activation energy are new aspects of this study. This article elaborates the effects of viscous dissipation, Cattaneo–Christov diffusion for Maxwell and Williamson nanofluid transportation that occurs due to porous stretching sheet. The higher order non-linear partial differential equations are solved by using similarity transformations and a new set of ordinary differential equations is formed. For numerical purpose, Runge–Kutta method with shooting technique is applied. Matlab plateform is used for computational procedure. The graphs for various profiles .i.e. velocity, temperature, concentration and concentration of motile micro-organisms are revealed for specific non-dimensional parameters. It is observed that enhancing the magnetic parameter M, the velocity of fluid decreases but opposite behavior happens for temperature, concentration and motile density profile. Also the motile density profile decrease down for Pe and Lb. The skin friction coefficient is enhanced for both the Williamson and Maxwell fluid.