In this paper, a problem o f flu id-structure interaction in a mixing vessel equipped with a Rushton turbine is solved with partitioned coupled fluid-structure interaction computational analysis. The co mputational flu id dynamics (CFD) code, based on the finite volu me method, is used for determination of the flow field in the mixing vessel. The results in form of pressure distribution are then applied to the blade model, which is then analy zed with the co mputational structure dynamics (CSD) code, based on the finite element method. The resulting displacement is evaluated. The proposed procedure can be effectively used for optimization of structures with significant fluid flow in fluences. The comparison of the velocity profile with the results founded in the literature shows a good comparison. This proves the validity of the numerical method.