Hydrothermal synthesis of PVP-passivated clove bud-derived carbon dots for antioxidant, catalysis, and cellular imaging applications

Pandey, Anurag Kumar; Bankoti, Kamakshi; Nath, T. K.; Dhara, Santanu

doi:10.1016/j.colsurfb.2022.112926

Cited by 15 publications

(4 citation statements)

References 62 publications

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“…CDs derived from cloves exhibited an IC 50 value (57 μg mL −1 ) (Pandey et al, 2022) similar to that obtained for CD-L and higher than that obtained for CD-oPD (Table 1). Clove-derived CDs were also assessed against O 2 C− and showed an IC 50 of 53 μg mL −1 (Pandey et al, 2022), indicating greater activity against this reactive species, compared to CD-L.…”

Section: Resultssupporting

confidence: 77%

Carbon dots-based fluorescent films to act as a potential antioxidant agent and pH ratiometric sensor for skin applications

Da Silva,

Araujo,

Almeida

et al. 2023

Front. Carbon

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The wound healing process is accompanied by changes in pH values. Monitoring this physicochemical parameter can indicate the effectiveness of the applied treatment and act as early identification of wound infection. This study focuses on the development of a fluorescent film-based polyvinyl alcohol (PVA) and carbon dots (CDs) derived from lemon bagasse (CD-L) and ortho-phenylenediamine (CD-oPD) named to act as antioxidants and potential ratiometric fluorescent pH sensors, in wound applications. The I460/I550 intensity ratio, as a function of pH value for the dual-system CDs prepared from the mixture of CD-L and CD-oPD, named CD-L/oPD, was investigated. The fit corresponded to a sigmoidal function in the pH range of 5–10, with a relationship having a r2 = 0.992. The variation in the values of the I460/I550 ratio allows for the visualization of the color change from yellowish-green to green with increasing pH. Through a simulated ex vivo pig skin model, it was possible to note that the films prepared from mixed of the CD-L and CD-oPD carbon dots incorporated in a matrix PVA named CD-L/oPD-F was more efficient at visually discriminating color in relation to changes in pH than the films prepared from both individual CD-L (CD-L-F) and CD-oPD (CD-oPD-F) carbon dots. CD-L and CD-oPD demonstrated antioxidant capacity against reactive oxygen species (ROS). The IC50 values for CD-L and CD-oPD were 56.7 and 39.5 μg mL−1 in the DPPH● inhibition assay, and 25.1 and 63.4 μg mL−1 in the HOCl scavenging one, respectively. MTT viability assays using human non-tumoral skin fibroblast (HFF-1) cell showed a cell survival rate of over 80% for both CDs up to a concentration of 1,000 μg mL−1. Finally, the developed films can act in a bifunctional way, by monitoring healing through pH changes and by acting as an antioxidant agent in the treatment of wounds.

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Section: Resultssupporting

confidence: 77%

Carbon dots-based fluorescent films to act as a potential antioxidant agent and pH ratiometric sensor for skin applications

Da Silva,

Araujo,

Almeida

et al. 2023

Front. Carbon

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“…In the biological system, generation of reactive oxygen species or free radicals is a critical phenomenon which has been showed to be altered by NPs with antioxidant activity. 56 As it is already known that carbon NPs have good semiconductor property with the capability to transfer or receive an electron, which implies them as potent candidate for manipulation of ROS in a biological system. 56 1,1-diphenyl-2-picryl-hydrazyl (DPPH • ) radical scavenging is a commonly used method for evaluating the antioxidant activity.…”

Section: Resultsmentioning

confidence: 99%

“… 56 As it is already known that carbon NPs have good semiconductor property with the capability to transfer or receive an electron, which implies them as potent candidate for manipulation of ROS in a biological system. 56 1,1-diphenyl-2-picryl-hydrazyl (DPPH • ) radical scavenging is a commonly used method for evaluating the antioxidant activity. Seven different concentrations of ND samples were tested ranging from 20 to 1000 μg/mL via the (DPPH • ) radical scavenging method.…”

Section: Resultsmentioning

confidence: 99%

Biocompatible Nanodiamonds Derived from Coal Washery Rejects: Antioxidant, Antiviral, and Phytotoxic Applications

et al. 2023

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Coal washery rejects (CWRs) are a major byproduct produced in coal washery industries. We have chemically derived biocompatible nanodiamonds (NDs) from CWRs toward a wide range of biological applications. The average particle sizes of the derived blueemitting NDs are found to be in the range of 2−3.5 nm. High-resolution transmission electron microscopy of the derived NDs depicts the crystalline structure with a d-spacing of 0.218 nm, which is attributed to the 100 lattice plane of a cubic diamond. The Fourier infrared spectroscopy, zeta potential, and X-ray photoelectron spectroscopy (XPS) data revealed that the NDs are substantially functionalized with oxygencontaining functional groups. Interestingly, the CWR-derived NDs exhibit strong antiviral properties (high inhibition of 99.3% with an IC 50 value of 7.664 μg/mL) and moderate antioxidant activity that widen the possibility of biomedical applications. In addition, toxicological effects of NDs on the wheatgrass seed germination and seedling growth showed minimal inhibition (<9%) at the highest tested concentration of 300.0 μg/mL. The study also provides intriguing prospects of CWRs for the creation of novel antiviral therapies.

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“…The XRD pattern and Raman spectrum were performed to examine the crystalline/graphitic structure of the prepared NN-CDs. Figure 3 a depicts the XRD pattern of the NN-CDs, revealing a broad peak around 2θ = 24.5°, which corresponded with the typical (0 0 2) diffraction peak of standard carbon/graphene [ 35 , 36 ]. The calculated d-spacing value of the NN-CDs was 0.36 nm, which was greater than that of a standard graphene interlayer spacing (0.34 nm, d-spacing), along with the broadness character.…”

Section: Resultsmentioning

confidence: 99%

Natural Nitrogen-Doped Carbon Dots Obtained from Hydrothermal Carbonization of Chebulic Myrobalan and Their Sensing Ability toward Heavy Metal Ions

Atchudan

Perumal

Edison

et al. 2023

Sensors

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Chebulic Myrobalan is the main ingredient in the Ayurvedic formulation Triphala, which is used for kidney and liver dysfunctions. Herein, natural nitrogen-doped carbon dots (NN-CDs) were prepared from the hydrothermal carbonization of Chebulic Myrobalan and were demonstrated to sense heavy metal ions in an aqueous medium. Briefly, the NN-CDs were developed from Chebulic Myrobalan by a single-step hydrothermal carbonization approach under a mild temperature (200 °C) without any capping and passivation agents. They were then thoroughly characterized to confirm their structural and optical properties. The resulting NN-CDs had small particles (average diameter: 2.5 ± 0.5 nm) with a narrow size distribution (1–4 nm) and a relatable degree of graphitization. They possessed bright and durable fluorescence with excitation-dependent emission behaviors. Further, the as-synthesized NN-CDs were a good fluorometric sensor for the detection of heavy metal ions in an aqueous medium. The NN-CDs showed sensitive and selective sensing platforms for Fe3+ ions; the detection limit was calculated to be 0.86 μM in the dynamic range of 5–25 μM of the ferric (Fe3+) ion concentration. Moreover, these NN-CDs could expand their application as a potential candidate for biomedical applications and offer a new method of hydrothermally carbonizing waste biomass.

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Hydrothermal synthesis of PVP-passivated clove bud-derived carbon dots for antioxidant, catalysis, and cellular imaging applications

Cited by 15 publications

References 62 publications

Carbon dots-based fluorescent films to act as a potential antioxidant agent and pH ratiometric sensor for skin applications

Carbon dots-based fluorescent films to act as a potential antioxidant agent and pH ratiometric sensor for skin applications

Biocompatible Nanodiamonds Derived from Coal Washery Rejects: Antioxidant, Antiviral, and Phytotoxic Applications

Natural Nitrogen-Doped Carbon Dots Obtained from Hydrothermal Carbonization of Chebulic Myrobalan and Their Sensing Ability toward Heavy Metal Ions

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