Hydroxyapatite formed from Coral Skeletal Carbonate by Hydrothermal Exchange

Roy, Della M.; Linnehan, Sari Kurtossy

doi:10.1038/247220a0

Cited by 628 publications

(310 citation statements)

References 8 publications

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“…The CaO so obtained from the eggshells was then converted into HAp in a phosphate solution following a procedure reported before by Roy [12], Eric M. Rivera et.al [8] and subsequently used by others [13].…”

Section: Methodsmentioning

confidence: 99%

Synthesis of Hydroxyapatite Bio-Ceramic Powder by Hydrothermal Method

Hui¹,

Meena²,

Singh³

et al. 2010

JMMCE

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Section: Methodsmentioning

confidence: 99%

Synthesis of Hydroxyapatite Bio-Ceramic Powder by Hydrothermal Method

Hui¹,

Meena²,

Singh³

et al. 2010

JMMCE

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“…Calcium sulphate and calcium phosphate compounds are attractive alternatives to autografts because of their excellent biocompatibility, handling characteristics, porosity, rate of dissolution, chemical and physical resemblance to bone mineral and potentially unlimited supply at a modest cost [10][11][12][13]. Calcium phosphate cements are one of the most widely used bone substitute [13,14].…”

Section: Introductionmentioning

confidence: 99%

Cranioplasty of Hemispherical Defects Using Calcium Phosphate Cements Along with Titanium Mesh: Our Experience

Kumar

Sudeep

Balwan

2015

J. Maxillofac. Oral Surg.

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Introduction Cranial defects may arise due to trauma, infection, surgical ablation or errors in development. Restoration of such defects is important for esthetics, function and morale of the patient. Several materials are available. Each has its advantages and disadvantages. Search is on for an ideal material. Autogenous grafts remain the gold standard in reconstruction of such defects. However, the morbidity associated with their harvest, additional time required, the need for a second surgical site and the limited supply has led to the search for newer substitutes. Although many materials are available today including biologic and non biologic substitutes, there is still no consensus about the best material. In this article we describe our use of calcium phosphate cements for reconstruction of hemispherical cranial defects. Materials and Methods Cases requiring reconstruction of hemispherical cranial defects (more than 15 cm in any dimension) were selected for study. After exposing the defect under GA, titanium mesh was adapted to the defect for support. Then the calcium phosphate cement was prepared and injected on the mesh to establish good contour. The alloplastic insert in each patient was evaluated for: (a) Immediate post-operative complications (b) Restoration of contour and soft tissue support (c) New bone formation ascertained on HRCT at the end of 2 years. Patients were examined on postoperative first week, at 3 and at 6 months.High resolution computed tomography scans were taken at 2 years postop. There were two female and three male patients. Results There were no complications in the post operative period. The general condition of the patients improved post operatively. Even though the cements maintained their contour at 2 years, there were no signs of bone formation within the cement. Conclusion Calcium phosphate cement is a good bone substitute for use in cranioplasty. In defects requiring mechanical strength, it should be supported by a titanium mesh. It retains the contour but is not replaced by bone even after 2 years.

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“…The coral species Porites astreoides was chosen because of its theoretically ideal pore size for the ingrowth of bone. On electron microscopic examination, the average pore size of Porites astreoides was found to be 153.95±25.36 µm [61,62].…”

Section: Ceramic Matricesmentioning

confidence: 99%

Clinical applications of bone graft substitutes in spine surgery: consideration of mineralized and demineralized preparations and growth factor supplementation

Berven

Tay

Kleinstueck

et al. 2001

European Spine Journal

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Introduction and backgroundTissue and mineral grafts in the spine perform mechanical and biologic functions. Their capacity for each function is dependent upon the structural, cellular, and biochemical properties of the particular graft chosen. Autogenous bone offers an optimal balance of osteogenic, osteoinductive, and osteoconductive capacities, structural stability, and biocompatibility. However, the availability of autogenous bone graft is clearly limited, and the complications of autogenous harvest are well known [6, 16, 17, 19, 23, 29, 30, 36, 46,78,95]. In choosing bone graft substitutes for clinical application, the spine surgeon's decision generally involves a compromise of mechanical and biological functional considerations. This article will address the clinical applications of mineralized and demineralized bone graft preparations in spinal surgery, reviewing the basic science and clinical experience supporting the use of these substitutes.A bone graft material is any implanted material that alone or in combination with other materials promotes a bone healing response by osteogenic, osteoconductive, or osteoinductive activity at a local site [56]. Graft material that is osteogenic contains viable cells at some stage of osteoblastic differentiation and is capable of forming new bone directly. Osteoinductive graft materials contain cytokines capable of inducing differentiation of host cells into bone forming cells. Osteoconductive graft materials provide a biocompatible matrix that supports new bone formation. Substitutes for autogenous bone graft may have variable capacities for each of these functions. In spinal surgery, the ideal bone graft substitute should be osteogenic, biocompatible, bioabsorbable, easy to use, and cost effective and should provide structural support. However, the success of a particular material in achieving these goals depends upon the material and biologic properties of the grafting material as well as the particular host environment in which it is placed. Abstract Bone graft substitutes may be broadly classified as mineralized and demineralized preparations. This article reviews the basic science and biology underlying each preparation. A review of the clinical and experimental applications of each preparation follows. The text concludes with a review of growth factors as biological supplements.

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Hydroxyapatite formed from Coral Skeletal Carbonate by Hydrothermal Exchange

Cited by 628 publications

References 8 publications

Synthesis of Hydroxyapatite Bio-Ceramic Powder by Hydrothermal Method

Synthesis of Hydroxyapatite Bio-Ceramic Powder by Hydrothermal Method

Cranioplasty of Hemispherical Defects Using Calcium Phosphate Cements Along with Titanium Mesh: Our Experience

Clinical applications of bone graft substitutes in spine surgery: consideration of mineralized and demineralized preparations and growth factor supplementation

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