Hydroxychloroquine Adsorption in Aqueous Medium Using Clinoptilolite Zeolite

Abstract

The presence of drugs on a large scale in aquatic matrices raises concern and requires the study of efficient technologies to remove these compounds. This study investigated the adsorption capacity of the natural zeolite clinoptilolite (CP) in removing the drug hydroxychloroquine (HCQ). Zeolite was characterized by BET, XRD, FT-IR, SEM, and pH pzc techniques. The kinetic model that best fits the experimental data was the pseudo-first-order and the SIPS isotherm provided the best fit. The Langmuir isotherm RL separation factor (> 0.01) indicated that the adsorption process was favorable and the Freundlich isotherm ( n > 1) suggested that the adsorption mechanism occurred mainly by physisorption, with intraparticle diffusion as the step limiting the process. The process was spontaneous (ΔG° ads < 0), endothermic (ΔH° ads > 0), and with increased randomness at the solid-solution interface (ΔS° ads > 0). The initial pH variation of the effluent was not favorable for the adsorption process and the zeolite was easily regenerated for later use. The ecotoxicological tests with Artemia salina and Lactuca Sativa proved that the final effluent did not show toxicity after the adsorption treatment. Based on the results obtained in this work, clinoptilolite zeolite is a potential adsorbent for reducing HCQ toxicity in aquatic matrices. Supplementary Information The online version contains supplementary material available at 10.1007/s11270-022-05787-3.

Degradation of hydroxychloroquine in aqueous solutions under electron beam treatment

“…Additionally, catalytic processes using titanium oxide containing beta bismuth oxide (-Bi 2 O 3 ) [12], sono-catalytic activity using the MoS 2 /CNTs nanocomposite [13], electrochemical oxidation using boron--doped diamond electrodes [14,15], Ti 3 GeC 2 with 0.15 mmol•L −1 of peroxydisulfate (PDS) under ultrasound irradiation [16], and the ZnO-CP catalyst [17] are popular alternatives. Adsorbents, such as: living microalgae [18], H 3 PO 4 activated Cystoseira barbata biochar from algal biodiesel industry waste [19], natural zeolite clinoptilolite (CP) that adsorbs HCQ with increasing effi ciency from pH 27.5 [20], and Algerian kaolin [21] have been studied for similar applications. Advanced oxidative processes (AOPs) utilize reactive hydroxyl radicals to degrade pollutants of emerging concern.…”

Selecting Catalysts for Pyrolysis of Lignocellulosic Biomass

“…The structures of zeolites can vary, as illustrated in Figure 5, and their connectivity can also vary due to the cages within the channel, in addition to the possible formation of one-dimensional, two-dimensional and three-dimensional channels [79]. Due to their great versatility, zeolites are used in many relevant industrial processes, such as adsorption [80], separation [81] and catalysis [82][83][84].…”

A Box-Behnken design-based chemometric approach to optimize the degradation of hydroxychloroquine in water media using the Fe(0)/S2O2-8/UV system

“…Because HCQ is a potentially recalcitrant and bioaccumulative substance and is produced in large quantities, it can be passed throughout the food chain from one organism to another in various forms, increasing the menace of its occurrence in the ecosystem. This provides it high potential to be the next emerging pharmaceutical pollutant and as a result of this real problem, many researchers have developed numerous treatment methods over the past years to limit its spread in aquatic environments including photocatalysis (Kargar et al 2021;Radwan et al 2022a), electrochemical oxidation (Bensalah et al 2020b;de Araújo et al 2022), mineralization by gamma-irradiation (Boujelbane et al 2022;Jebali and Jelassi 2022), sonocatalytic degradation (Dastborhan et al 2022), Ultrasound-assisted catalytic oxidation (Ansarian et al 2022), advanced oxidation processes (Guo et al 2022;Huang et al 2022), adsorption (Bendjeffal et al 2021;Gümüş and Gümüş 2022;Picoli et al 2022). However, many of these techniques are either not very effective or too expensive, especially when applied to the treatment of large water flows.…”

“…This technique must be used upstream before wastewater and HCQ are released into natural aquatic environments. Fenton techniques are among the most promising and cost-effective methods of eliminate drugs and their derivatives from aqueous media (Neuwoehner et al 2009;Bensalah et al 2020a;Bendjeffal et al 2021;Ansarian et al 2022;Gümüş and Gümüş 2022;Guo et al 2022;Huang et al 2022;Picoli et al 2022). Recently, the Fenton method and its analogs (e.g.…”