25This work focuses on the study of aerosol hygroscopic growth during Sierra Nevada Lidar AerOsol Profiling Experiment (SLOPE I) campaign by using the synergy of active and passive remote sensors at Granada valley station (IISTA-CEAMA station) and in-situ instrumentation at a mountain station (Sierra Nevada station, SNS), located ~20 km away from IISTA-CEAMA and about 1 km above this station. To this end, a methodology based on the combination of calibrated water vapour mixing ratio ( ) profiles, retrieved from an EARLINET multiwavelength Raman lidar (RL), and continuous temperature 30 profiles from a microwave radiometer (MWR) for obtaining relative humidity ( ) profiles with high temporal resolution is used. This methodology is validated against an approach using radiosounding (RS) data at the EARLINET IISTA-CEAMA station, achieving differences in hygroscopic growth parameter ( ) lower than 5% between the methodology based on RS and that based on remote sensing. During SLOPE I the remote sensing methodology used for aerosol hygroscopic growth studies has been checked using Mie calculations with in-situ measurements at SNS. For SLOPE I case with remote sensing 35 instrumentation, an increase in particle backscatter coefficient at 355 and 532 nm is observed from 1.5 to 2.4 km a.s.l. in the 2 relative humidity range of 78-98%, but also a decrease on Ångström exponent (AE) and particle linear depolarization ratio (PLDR). This fact indicates that particles become larger and more spherical as relative humidity increases, what is strongly related to aerosol hygroscopic growth. In addition, atmospheric stability is checked ensuring well-mixed layers.Vertical and horizontal wind analysis is performed by means of a co-located Doppler lidar system at IISTA-CEAMA station, in order to evaluate the horizontal and vertical dynamics of the air masses. Finally, the Hänel parameterization is applied to 5 experimental data for both stations, obtaining relative differences between RL and Mie simulations up to 13 % and 10 % for 532 nm and 355 nm, respectively.