Hymenaea stigonocarpa Mart. ex Hayne: A tropical medicinal plant with intestinal anti-inflammatory activity in TNBS model of intestinal inflammation in rats

Orsi, Patrícia Rodrigues; Seito, Leonardo Noboru; Stasi, Luiz Cláudio Di

doi:10.1016/j.jep.2013.10.056

Cited by 41 publications

(26 citation statements)

References 38 publications

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“…The fruits of Hymenaea stigonocarpa (Fabaceae), exhibit anti-inflammatory and antioxidant effects in intestinal diseases of rats (Orsi, Seito & Di Stasi, 2014). These effects can be explained by the presence of the flavonoid, myricetin, present in the composition of the seeds, as identified in this study.…”

Section: Resultssupporting

confidence: 58%

Content of phenolic compounds in fruit processing residues by mass spectrometry

Vagula¹,

Visentainer²,

Lopes³

et al. 2019

Acta Sci. Technol.

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This study identified and quantified five phenolic compounds, and evaluated the antioxidant capacity in vitro of fifteen native and exotic Brazilian fruit seeds that are typically discarded as waste. The contents of phenolic compounds were determined by ultra-performance liquid chromatography coupled with tandem mass spectrometry, and the antioxidant capacity was determined by oxygen radical absorbance capacity (ORAC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH•) antioxidant assays. The results showed the antioxidant activity of Campomanesia pubescens, Hovenia dulcis Thunberg and Syzygium jambos (L.) Alston in the ORAC assay, and Hymenaea stigonocarpa, Hovenia dulcis Thunberg and Campomanesia pubescens in the DPPH• assay. Among the fifteen samples, four were highlighted regarding phenolic compound analyzes: Hovenia dulcis Thunberg (5.723 µg g-1) for gallic acid and myricetin (111.057 µg g-1), Passiflora edulis (1.208 µg g-1) for chlorogenic acid, Annona atemoya (1.0580 µg g-1) for vanillic acid, and Campomanesia pubescens (0.420 µg g-1) for ferulic acid. Therefore, these fruit seeds can be used as alternative sources of natural antioxidants.

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Section: Resultssupporting

confidence: 58%

Content of phenolic compounds in fruit processing residues by mass spectrometry

Vagula¹,

Visentainer²,

Lopes³

et al. 2019

Acta Sci. Technol.

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“…The same findings were reported in animal models of trinitrobenzenesulfonic acid-induced ulcer (Drsi et al, 2014), justifying the need to determine the antioxidant activity of this fruit. Moreover, jatobá is already commonly used in the treatment of certain diseases related to oxidative stress, and its potential in the prevention of such diseases has not yet been explored.…”

Section: Introductionsupporting

confidence: 70%

In vitro and in vivo antioxidant activity of the pulp of Jatobá-do-cerrado

et al. 2016

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Dxygen metabolism in cells causes the production of free radicals, which produce damage, including changes in cell structure and function. Antioxidants are substances that, at low concentrations, slow down or prevent oxidation. Fruits and vegetables contribute to the dietary supply of these compounds. The flora of the Cerrado in Brazil has shown to have high levels of bioactive compounds. This study aimed to characterize the antioxidant activity of the pulp of jatobá-do-cerrado in vitro and in vivo. In vitro antioxidant activity of the aqueous, ethanol and aqueous acetone extracts was evaluated by the DPPH method. We determined total phenols by the Folin-Ciocalteu assay and tannins by the Folin-Denis method. In vivo antioxidant potential of the aqueous acetone extract was evaluated by the TBARS technique. The aqueous acetone extract had the highest antioxidant capacity, followed by the aqueous and ethanol extracts. The same pattern occurred in the extraction of phenols and in the extraction of tannins. In vivo administration of the aqueous acetone extract inhibited lipid peroxidation compared to the control group. The inhibition of peroxidation has increased by elevating the dosage concentration of the extracts, demonstrating a significant antioxidant potential in vivo as well as in vitro.

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“…Phenolic compounds in particular, such as flavonoids [42][43][44][45], coumarin derivatives [24,[46][47][48] and some medicinal plant extracts [49][50][51], have been shown to have significant effects. In fact, medicinal plants represent an invaluable source of substances with antioxidant and immunomodulatory properties [52,53].…”

Section: Discussionmentioning

confidence: 99%