Hyperbaric oxygen therapy does not improve the effects of standardized treatment in a severe attack of ulcerative colitis: a prospective randomized study

Pagoldh, Maria; Hultgren, Elin; Arnell, Per; Eriksson, Anders

doi:10.3109/00365521.2013.819443

Cited by 24 publications

(45 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The median full Mayo score declined more in the HBOT group (control group = 11 points pre‐treatment to 3 points post‐treatment, HBOT group = 11 points pre‐treatment to 0.5 points post‐treatment), but this difference was not statistically significant. There were no differences in faecal calprotectin, health‐related quality of life, or other study parameters …”

Section: Resultsmentioning

confidence: 86%

“…Of those, 271 were excluded after reviewing titles and abstracts. Subsequently, 42 papers were retrieved in full text of which 17 studies were included in our final analysis . (Figure ) Eleven were case reports (<5 patients), three were case series (≥5 patients) or cohort studies, two were case–control studies and one was a randomised controlled trial …”

Section: Resultsmentioning

confidence: 99%

“…The one remaining UC study by Pagoldh et al . carried the highest risk of bias among included studies.…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Systematic review: the safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease

Dulai

Gleeson

Taylor

et al. 2014

Aliment Pharmacol Ther

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 86%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Systematic review: the safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease

Dulai

Gleeson

Taylor

et al. 2014

Aliment Pharmacol Ther

View full text Add to dashboard Cite

show abstract

“…This is solely because of the fact that the sampling was performed in parallel to the protocol of the hyperbaric oxygen therapy study [33], which was prematurely ended owing to lack of clinical benefits (in accordance with the interim analysis). Following this decision, further sampling in this part of the project was ended.…”

Section: Discussionmentioning

confidence: 96%

Faecal analysis and plasma complement factor 3c levels at admission for an acute attack of ulcerative colitis are predictive of the need for colectomy

Pagoldh¹,

Lange²,

Jennische³

et al. 2014

European Journal of Gastroenterology & Hepatology

Self Cite

View full text Add to dashboard Cite

show abstract

“…HBOT is mostly performed in developed countries, such as USA and UK. According to SF-36 instrument, HBOT improves vitality, physical function, body pain, total health perceptions, mental health and physical, emotional, and social role functioning in patients with troublesome diseases (15,17,19,21,27).…”

Section: Discussionmentioning

confidence: 99%

Hyperbaric Oxygen Therapy and Quality of Life: A Systematic Review

Nourmohammadi

Doaee

Fazel

et al. 2017

Ann Mil Health Sci Res

View full text Add to dashboard Cite

Objective: Hyperbaric oxygen therapy (HBOT) involves breathing pure oxygen in a high-pressure chamber. HBOT is a wellestablished treatment for several diseases, such as serious infections, chronic diabetic foot ulcer, radiation injury, and hidradenitis suppurativa. There are various troublesome diseases that decrease pleasure in life in patients. HBOT has excellent effects in improving QOL in patients with acute and chronic diseases. The present study aimed at assessing the researches that focus on improving the QOL after HBO treatments. Methods:A systematic quest was conducted to evaluate English papers (clinical trials) that were published before April 2017. We searched PubMed, institute of scientific information (ISI), SCOPUS, Web of Science, Ovid, Science direct, ProQuest, Wiley, Cochran, Ebsco host, and Google Scholar. The reference lists of all the articles and electronic journals were searched for further studies. The JAMA users guide evaluation scales for RCTs was used to assess quality of the researched articles. Inclusion and exclusion criteria were extracted according to the scientific criteria. Sample size was 806 patients.Results: Finally, 15 published articles were extracted. Most researches were done in UK (26.7%), Israel (20%), and Sweden (20%). The mean age in HBOT group was 41.88, with a male to female ratio of 1.52. The mean age in the control group was 38.29, with a male to female ratio of 2.14. The most frequent clinical trials were those on the treatment of diabetic foot ulcer (20%), post-concussion syndrome (13.3%), pelvic radiotherapy (13.3%), and chronic arm lymphedema after radiotherapy (13.3%). The most QOL questionnaires used were SF-36 (21.4%), EORTC (European organization for research and treatment of cancer) QLQ-C30, head and neck cancer module (H&N35), and performance status scale (PSS).Conclusions: A significant effect of HBOT on improving QOL in patients' outcomes and symptoms was found compared with the control group. We found improved QOL in patients with diabetic foot ulcer, post-concussion syndrome, pelvic radiotherapy, post stroke, hidradenitis suppurativa, tonsillar fossa tumor radiotherapy, jaw osteonecrosis, and fibromyalgia syndrome. We suggest that HBOT be added to conventional treatment of these patients as an adjuvant.

show abstract

Hyperbaric oxygen therapy does not improve the effects of standardized treatment in a severe attack of ulcerative colitis: a prospective randomized study

Abstract: The study results do not support the use of HBOT as a treatment option in a severe attack of UC.

Cited by 24 publications

References 28 publications

Systematic review: the safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease

Systematic review: the safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease

Faecal analysis and plasma complement factor 3c levels at admission for an acute attack of ulcerative colitis are predictive of the need for colectomy

Hyperbaric Oxygen Therapy and Quality of Life: A Systematic Review

Contact Info

Product

Resources

About