Hyperbaric oxygen therapy for acute domestic carbon monoxide poisoning: two randomized controlled trials

Annane, Djillali; Chadda, Karim; Gajdos, Philippe; Jars-Guincestre, M. C.; Chevret, Sylvie; Raphaël, Jean-Claude

doi:10.1007/s00134-010-2093-0

Cited by 127 publications

(102 citation statements)

References 12 publications

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“…Current evidence from literature does not suggest a firm and definite benefit from HBO for carbon monoxide victims [4]. The findings from our trials are in line with the conclusions of the Cochrane review [2]. Drs.…”

supporting

confidence: 74%

“…Birmingham and Hoffman [1] raised some concerns about the validity of the reports from two randomized controlled trials which failed to show evidence of substantial benefit from hyperbaric oxygen therapy (HBO) for domestic carbon poisoning [2]. They argued that the main effect of HBO in case of carbon monoxide poisoning is to inhibit b2 integrins mediated adherence of neutrophils to the injured central nervous system (CNS) endothelium, and that this effect occurs only for at least 2.8-3 ATA [3].…”

mentioning

confidence: 99%

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Hyperbaric oxygen therapy for acute domestic carbon monoxide poisoning: two randomized controlled trials: reply to comment by Birmingham and Hoffman

2011

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supporting

confidence: 74%

mentioning

confidence: 99%

Hyperbaric oxygen therapy for acute domestic carbon monoxide poisoning: two randomized controlled trials: reply to comment by Birmingham and Hoffman

2011

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“…It is a colorless and odorless gas that binds to hemoglobin and cellular oxidative enzymes with a higher affinity than oxygen, causing tissue hypoxia. Hypoxia of heart and nervous system cells leads to neuropsychiatric and cardiological signs and symptoms (3). Patients diagnosed with carbon monoxide poisoning are discharged from the emergency department in about 90% of cases (4).…”

Section: Introductionmentioning

confidence: 99%

The Analysis of Carbon Monoxide Poisoning Cases Presented to the Emergency Department of a University Hospital

Coşkun

Kayıpmaz

Özbay

et al. 2016

Kırıkkale Üniversitesi Tıp Fakültesi Dergisi

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ÖZIntroduction: Carbon monoxide poisoning is one of the most leading poisoning causing death through worldwide, although its exact incidence is yet to be determined. Carbon monoxide is a colorless and odorless gas that binds to hemoglobin and cellular oxidative enzymes with a higher affinity than oxygen, causing tissue hypoxia. Hypoxia of heart and nervous system cells leads to neuropsychiatric and cardiological signs and symptoms. In this study, we aimed to investigate the demographic characteristics of the carbon monoxide poisonings occurring in patients presenting to the emergency department. We also aimed to determine the clinical characteristics, and the factors affecting the mortality.

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“…Symptoms may include headache, dizziness, nausea, vomiting, disorientation and unconsciousness. Moreover, CO poisoning can cause immediate death, non-specific hypoxia-related neurological and cardiac manifestations, rhabdomyolysis and abnormal liver function (4,5). Due to the hidden and mysterious nature of the disease, the clinical signs and symptoms of the exposure may easily be misdiagnosed in emergency departments.…”

Section: Introductionmentioning

confidence: 99%

Carbon Monoxide Poisoning: From the Perspective of Ten Years and 2417 Cases

Doğan¹,

Aksel²,

Güler³

et al. 2012

JAEM

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Objective: Carbon monoxide (CO) poisoning is a common problem in various countries, especially in Winter months. CO exposure results in the formation of carboxyhemoglobin (COHb), which is responsible for toxicity symptoms. In this study, we aim to demonstrate the demographic features and seasonal variations of this particular public health problem. Materials and Methods:We retrospectively evaluated hospital police reports and medical records of 2417 ED patients diagnosed with CO poisoning between 1999 and 2009. Sources of exposure, seasonal variation and demographic characteristics were analyzed. Results: The mean age of the patients, of whom 1418 (58.7%) were female, was 29±18 years. While 1708 patients (70.7%) were admitted to adult ED, 709 (29.3%) patients were admitted to pediatric ED. January and subsequent Winter months represented the most dangerous periods for CO exposure. No intentional (suicidal attempt) exposure to CO intoxication was reported and the major cause for intoxication included unsecured stoves and gas heaters. Conclusion: Emergency physicians should be familiar with symptoms and remedies of CO intoxication, which still constitutes a serious health problem. (JAEM 2012; 11: 157-60)

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Hyperbaric oxygen therapy for acute domestic carbon monoxide poisoning: two randomized controlled trials

Abstract: In patients with transient loss of consciousness, there was no evidence of superiority of HBO over NBO. In comatose patients, two HBO sessions were associated with worse outcomes than one HBO session.

Cited by 127 publications

References 12 publications

Hyperbaric oxygen therapy for acute domestic carbon monoxide poisoning: two randomized controlled trials: reply to comment by Birmingham and Hoffman

Hyperbaric oxygen therapy for acute domestic carbon monoxide poisoning: two randomized controlled trials: reply to comment by Birmingham and Hoffman

The Analysis of Carbon Monoxide Poisoning Cases Presented to the Emergency Department of a University Hospital

Carbon Monoxide Poisoning: From the Perspective of Ten Years and 2417 Cases

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