Hyperbaric Oxygen Therapy in the Pediatric Patient: The Experience of the Israel Naval Medical Institute

Waisman, Dan; Shupak, Avi; Weisz, Giora; Melamed, Yuval

doi:10.1542/peds.102.5.e53

Cited by 69 publications

(52 citation statements)

References 62 publications

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“…It was not felt that the HBO therapy modified the outcome in these patients, probably because a hyperoxygenated patient is not the solution to a condition mainly due to distal thrombosis. Waisman et al report a favorable experience in children treated with HBO [18]. Recently, HBO has been described as a conservative surgical management of soft tissue necrosis in a baby [19].…”

Section: Discussionmentioning

confidence: 99%

Meningococcal purpura fulminans in children: I. Initial orthopedic management

Nectoux

Mezel

Raux

et al. 2010

Journal of Children's Orthopaedics

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Background Purpura fulminans is a rare and extremely severe infection, mostly due to Neisseria meningitidis frequently causing early orthopedic lesions. Few studies have reported on the initial surgical management of acute purpura fulminans. The aim of this study is to look at the predictive factors in orthopedic outcome in light of the initial surgical management in children surviving initial resuscitation. Methods Nineteen patients referred to our institution between 1987 and 2005 were taken care of at the very beginning of the purpura fulminans. All cases were retrospectively reviewed so as to collect information on the total skin necrosis, vascular insufficiency, gangrene, and total duration of vasopressive treatment.

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Section: Discussionmentioning

confidence: 99%

Meningococcal purpura fulminans in children: I. Initial orthopedic management

Nectoux

Mezel

Raux

et al. 2010

Journal of Children's Orthopaedics

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“…4,5 The use of HBOT has been shown by several investigators to restore a favorable cellular environment for wound healing and support vascular proliferation by increasing the oxygen content of the plasma. 6,7 HBOT is currently widely used for treatment of CO intoxication, arterial gas emboli, compromised skin flaps and grafts, radiation soft tissue necrosis, osteoradionecrosis and chronic non-healing wounds. Siraneci et al 8 report the successful use of adjunctive HBOT in an infant with thrombotic purpura fulminans.…”

Section: Case Presentationmentioning

confidence: 99%

Hyperbaric oxygen in treatment of neonatal arterial thromboembolism of lower extremities

et al. 2006

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Arterial thromboembolism (TE) in the absence of current or recent history of a central catheter is a rare condition in newborn period. We report a case of severe lower extremities arterial TE of unclear etiology in a full-term neonate. By adding hyperbaric oxygenation to thrombolytic and antithrombotic therapy, we achieved improved perfusion of the upper leg tissues, preserving the knee and enabling below-the-knee amputation.

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“…[3][4][5] Treating critically ill small babies in a hyper- baric chamber poses special challenges and there is little published experience of these situations, 6 especially pertaining to children with cyanotic congenital heart disease (CCHD). [7][8][9] We describe HBOT of an infant with complex CCHD and CAGE.…”

Section: éLéments Cliniques : Un Bébé De Quatre Mois De Sexe Masculimentioning

confidence: 99%

“…However, if suspected on clinical grounds HBOT should not be delayed for these investigations 19 since physiologic considerations and clinical experience suggest that delays result in a worse outcome. 2,8,12,19,20 Unstable infants with CCHD are usually cared for in tertiary care centres where HBOT is readily available. If air transportation is necessary a fixed wing aircraft must be pressurized to 1 atmosphere absolute (ATA) or a helicopter must fly below 300 m to avoid bubble expansion and clinical deterioration.…”

Section: éLéments Cliniques : Un Bébé De Quatre Mois De Sexe Masculimentioning

confidence: 99%

Hyperbaric treatment of cerebral air embolism in an infant with cyanotic congenital heart disease

LeDez

Zbitnew

2005

Can J Anesth/J Can Anesth

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P Pu ur rp po os se e: : Infants with cyanotic congenital heart disease are at risk for cerebral arterial gas embolism (CAGE) from iv infusion lines. Concern about the hazards and difficulty of caring for such patients inside a hyperbaric chamber may deter referral. We report a complex case in which a small infant was managed successfully using a modified hyperbaric oxygen treatment (HBOT) schedule.C Cl li in ni ic ca al l f fe ea at tu ur re es s: : A four-month-old 6.19 kg male infant with a recent Glenn shunt for double-outlet right ventricle had a seizure and became unstable immediately after an iv drug infusion. The patient was sedated, intubated and ventilated and dobutamine was commenced. A computerized tomography (CT) scan performed ten hours later demonstrated three intracranial air bubbles. About ten hours later the patient was referred for HBOT which commenced soon afterwards in a multiplace chamber. Since the rightto-left shunt would greatly increase the risk of decompression illness from breathing hyperbaric air HBOT was modified by the use of an abbreviated schedule at reduced pressure. Two 90-min HBOT sessions were administered within 24 hr at 38 feet of seawater pressure, equivalent to 2.15 atmospheres absolute without any air break. During treatment the infant was ventilated using an Oxford Penlon ventilator. A subsequent CT scan demonstrated the absence of air. After extubation he appeared neurologically intact except for some weakness of the left arm.C Co on nc cl lu us si io on n: : Hyperbaric oxygen may be utilized to treat CAGE in small infants with right-to-left shunt and should be commenced promptly.

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Hyperbaric Oxygen Therapy in the Pediatric Patient: The Experience of the Israel Naval Medical Institute

Cited by 69 publications

References 62 publications

Meningococcal purpura fulminans in children: I. Initial orthopedic management

Meningococcal purpura fulminans in children: I. Initial orthopedic management

Hyperbaric oxygen in treatment of neonatal arterial thromboembolism of lower extremities

Hyperbaric treatment of cerebral air embolism in an infant with cyanotic congenital heart disease

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