Hyperchloremic acidosis post cardiac surgery and role of cardioplegia; an audit cycle

Intravenous Fluids and Hyperchloremia in Cardiac Surgery: Not the End of the Story?

“…A point of interest was the role of a cardioplegia solution unique in cardiac surgery requiring the use of CPB, which may explain the association between duration of CPB with peak perioperative S Cl À and hyperchloremia found in the study by McIlroy et al An audit by Karattuparambil et al also found a direct relationship between hyperchloremia and volume of cardioplegia solution used, although it is important to note that the type of cardioplegia solution may differ among institutions. 12 However, results from the study by McIlroy et al have to be interpreted with caution. Being a post-hoc secondary analysis study, results only were indicative of association and not causation between the potential perioperative variables and peak S Cl À concentrations.…”