1993
DOI: 10.1016/0021-9150(93)90049-z
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Hypercholesterolemia in non-insulin-dependent diabetes mellitus: different effect of simvastatin on VLDL and LDL cholesterol levels

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Cited by 28 publications
(14 citation statements)
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“…This reduction is of the same magnitude as that found in studies of atorvastatin in nondiabetic hypercholesterolemic and hypertriglyceridemic patients (18,19). Compared with studies of simvastatin 40 mg in patients with type 2 diabetes, we found a larger reduction in total cholesterol level (39 vs. 30%) and LDL cholesterol level (52 vs. 24 -42%) (20,29).…”
Section: Commentsupporting
confidence: 71%
“…This reduction is of the same magnitude as that found in studies of atorvastatin in nondiabetic hypercholesterolemic and hypertriglyceridemic patients (18,19). Compared with studies of simvastatin 40 mg in patients with type 2 diabetes, we found a larger reduction in total cholesterol level (39 vs. 30%) and LDL cholesterol level (52 vs. 24 -42%) (20,29).…”
Section: Commentsupporting
confidence: 71%
“…HDL-C levels increased significantly during simvastatin treatment. These effects of statins on plasma levels of lipids, lipoproteins, and apoB are consistent with several other studies in patients with dyslipidemia and T2DM (35)(36)(37).…”
Section: Discussionsupporting
confidence: 92%
“…The association between non-insulin-dependent DM and increased triglyceride, LDL-cholesterol and decreased HDLcholesterol levels are established as a fact. 29 Furthermore, results of a 22-year follow-up of healthy men showed that FBG values appeared to be an important independent predictor of cardiovascular death in nondiabetic apparently healthy middle-aged men. Therefore, to control the risk derived from the high blood cholesterol, FBG even among health population should be managed.…”
Section: Discussionmentioning
confidence: 98%