In this article, we show that for any non-isotrivial family of abelian varieties over a rational base with big monodromy, those members that have adelic Galois representation with image as large as possible form a density-1 subset. Our results can be applied to a number of interesting families of abelian varieties, such as rational families dominating the moduli of Jacobians of hyperelliptic curves, trigonal curves, or plane curves. As a consequence, we prove that for any dimension g ≥ 3, there are infinitely many abelian varieties over Q with adelic Galois representation having image equal to all of GSp 2g ( Z).