Hypereosinophilic Syndrome: A rare case of Loeffler’s endocarditis documented in cardiac MRI

Kleinfeldt, Tilo; Ince, Hueseyin; Nienaber, Christoph

doi:10.1016/j.ijcard.2009.03.059

Cited by 23 publications

(31 citation statements)

References 7 publications

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“…In this situation, it seems significant to differentiate between true myocardial infarction with other cardiac conditions mimicking myocardial infarction, like the second case. To a lesser degree, EGPA patients represent with subendocardial involvements …”

Section: Discussionmentioning

confidence: 99%

“…For the evaluation of cardiac involvements, echocardiography has long been a widely used imaging modality for quantification of chamber size, wall thickness as well as detection of thrombosis formation, and valvular involvements . It was suggested that echocardiography should be performed mandatory in all patients either with HES or EGPA .…”

Section: Discussionmentioning

confidence: 99%

“…5,6 Loeffler endocarditis is characterized by fibrous thickening of the endocardium, thrombus formation, and final development of restrictive cardiomyopathy secondary to endomyocardium eosinophilic infiltration. 7 On the contrary, EGPA patients often present with myocarditis, pericarditis, and progressive restrictive cardiomyopathy from vasculitic pathology of epicardial coronary artery, small intraluminal artery, or direct infiltration of myocardium by eosinophils or toxic mediator released by eosinophils. 6 Moreover, EGPA patients can present with sign of myocardial infarction from vasculitic pathology as well as acceleration of existing coronary atherosclerosis or both.…”

Section: Discussionmentioning

confidence: 99%

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Cardiac involvements in hypereosinophilia‐associated syndrome: Case reports and a little review of the literature

Jin

Liu

et al. 2017

Echocardiography

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Hypereosinophilia-associated syndrome is a rare group of systemic diseases without certain underlying causes. Hypereosinophilic syndrome (HES) and eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss syndrome (CSS), are initial considerations, when underlying causes remains unexplained despite of complete evaluation of hypereosinophilia. In this study, we report two rare cases, one case of HES with Loeffler endocarditis, and the other one of EGPA with restrictive cardiomyopathy mimicking myocardial infarction, to further address differential chief cardiac manifestations between HES and EGPA. Key roles of echocardiography played in detection of cardiac involvements, diagnosis, and prognosis prediction are also highlighted.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Cardiac involvements in hypereosinophilia‐associated syndrome: Case reports and a little review of the literature

Jin

Liu

et al. 2017

Echocardiography

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“…6). EMF is well depicted by cardiac MRI, and cine sequences are useful to demonstrate diastolic dysfunction [45][46][47][48] (Fig. 8).…”

Section: Fibrotic (Scarring) Stagementioning

confidence: 99%

Eosinophilic cardiac disease: Molecular, clinical and imaging aspects

Séguéla

Iriart

Acar

et al. 2015

Archives of Cardiovascular Diseases

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Eosinophilia may be responsible for cardiac injuries of widely varying severity, from acute myocarditis to endomyocardial fibrosis. In this review, we present both the molecular mechanisms that are responsible for these lesions and their clinical and paraclinical aspects. Numerous aetiologies can lead to severe eosinophilia, but these are mainly represented by hypersensitivity reactions, rheumatological diseases and hypereosinophilic syndrome. Because cardiac involvement may be extremely severe, echocardiography should be always performed in the context of eosinophilia and appropriate therapeutics should be started rapidly in order to limit the progression of the disease.

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“…Despite the progress in its knowledge and treatment, infective endocarditis [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] remains a therapeutic challenge [17]. We present a case of an infective endocarditis in a 62-year-old Italian man.…”

mentioning

confidence: 99%