Hypermetabolic Subserosal Uterine Leiomyoma With Synchronous Atypical Multiple Myeloma Mimicking Ovarian Malignancy With Multiple Bone Metastases on 18F-FDG PET/CT

Abstract

Subserosal cystic myoma with intense FDG uptake can resemble malignant cystic ovarian tumor and may lead to a false-positive diagnosis. A 49-year-old woman presented with chest pain for 4 months, and the initial chest CT showed multiple bone lesions. 18 F-FDG PET/CT revealed not only multiple osteolytic lesions with FDG uptake but also a highly FDG-avid mass abutting the right side of the uterus. Ovarian malignancy with multiple bone metastases was considered initially. Subsequent biopsy confirmed multiple myeloma, and a subserosal uterine myoma was diagnosed by transvaginal sonography.

Massive Hepatocellular Carcinoma Combined With Giant Uterine Fibroid on 18F-FDG PET/CT

“…7 However, hypermetabolic uterine fibroid is prone to be misdiagnosed as malignancy, 8 especially in patients with primary malignant tumor. 9 We present a rare case of an asymptomatic woman with massive hepatocellular carcinoma and simultaneous giant uterine fibroid instead of metastasis, where PET/CT helped in making the correct diagnosis. AFP, alpha-fetoprotein.…”