Hyperplasia of rib and vertebra, associated with infiltrating lipoma: a rare case of focal overgrowth

Poorter, Jolanda J. de; Kroon, Herman M.; Dijkstra, Sander

doi:10.1007/s00586-014-3506-5

Cited by 4 publications

(3 citation statements)

References 7 publications

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“…In an effort to challenge our hypothesis, we retrieved the MR images from the most recent case in the literature. 3 We found several striking similarities between their case (Fig. 3), our current case (Fig.…”

Section: Literature Reviewsupporting

confidence: 80%

“…Of these, 15 noted lipomas, spinal epidural lipomatosis, or lipomatosis affecting spinal nerves. We identified 3 cases, 3,6,11 including one by our group 6 demonstrating segmental thoracic lipomatosis with osseous hypertrophy and fatty infiltration of paraspinal muscles. Two cases had MRI evidence of fat encasing thoracic spinal nerves.…”

Section: Literature Reviewmentioning

confidence: 99%

“…Two cases had MRI evidence of fat encasing thoracic spinal nerves. 3,6 In one case, 11 MRI was not available, but the segmental pattern of bony overgrowth, together with the infiltration of fat into a subcutaneous/intermuscular compartment within the territory of the T-6 spinal nerve, would be consistent with LN. None of these 3 patients experienced symptoms from thoracic spinal nerve compression.…”

Section: Literature Reviewmentioning

confidence: 99%

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A new pattern of lipomatosis of nerve: case report

Prasad¹,

Mahan

Howe

et al. 2017

JNS

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Lipomatosis of nerve (LN) is a rare disorder of peripheral nerves that produces proliferation of interfascicular adipose tissue. It may be associated with soft-tissue and bony overgrowth within the affected nerve territory. LN has been almost exclusively reported in appendicular peripheral nerves; the median nerve at the wrist and palm is among the most common locations. The authors present a new pattern of LN that shows circumferential proliferation of fat around the epineurium of the nerve. They believe that this case and the two other documented examples in the literature (also affecting cervical and thoracic spinal nerves) share the same new pattern of LN. Defining the full spectrum of adipose lesions of the nerve and establishing a cause-effect relationship with nerve-territory overgrowth disorders may offer options for future management through targeted nerve lesioning.

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Section: Literature Reviewsupporting

confidence: 80%

Section: Literature Reviewmentioning

confidence: 99%

Section: Literature Reviewmentioning

confidence: 99%

See 1 more Smart Citation

A new pattern of lipomatosis of nerve: case report

Prasad¹,

Mahan

Howe

et al. 2017

JNS

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Can Lipomatosis of the Nerve Occur or Extend Intradurally?

et al. 2019

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Macrodystrophia Lipomatosa of Thoracic Spine Causing Progressive Neurodeficit

Jakkepally

Viswanathan

Shetty

et al. 2021

JBJS Case Connector

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Case: We report the first case of a 21-year-old male patient with macrodystrophia lipomatosa (MDL), with local gigantism involving the thoracic spine and progressively worsening neurodeficit. Imaging studies revealed fatty infiltration and hypertrophied intercostal nerves, dextroscoliosis, osseous hypertrophy between C4 and T2, and severe canal stenosis at the T4 to T5 level secondary to lamino-facetal hypertrophy. He underwent debulking of the lesion and posterior instrumented decompression in a staged manner. His neurodeficit improved postoperatively and was ambulant without support at the end of the 2-year follow-up. Conclusion: Surgery in patients with MDL is technically challenging and fraught with complications such as neurological deficit and significant blood loss.

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Hyperplasia of rib and vertebra, associated with infiltrating lipoma: a rare case of focal overgrowth

Abstract: We report on a second case of focal overgrowth of a rib and half of the adjacent vertebra, and overlying lipoma. In addition to the first case, we present MR images demonstrating infiltration of the adipose tissue.

Cited by 4 publications

References 7 publications

A new pattern of lipomatosis of nerve: case report

A new pattern of lipomatosis of nerve: case report

Can Lipomatosis of the Nerve Occur or Extend Intradurally?

Macrodystrophia Lipomatosa of Thoracic Spine Causing Progressive Neurodeficit

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