Hypersensibilité retardée aux tatouages induite par un traitement combiné anti-BRAF/anti-MEK

Rohmer, E.; Scrivener, J.-N.; Schissler, C.; Cribier, B.; Lenormand, C.

doi:10.1016/j.annder.2019.08.012

Cited by 4 publications

(3 citation statements)

References 21 publications

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“…15 Besides, several cases of granulomatous tattoo reactions under BRAF and MEK inhibitors have been reported. [48][49][50] They illustrate that immunity modulation can lead to a localized reaction against tattoos: the tattoos are the target, but not the cause of the reaction.…”

Section: Discussionmentioning

confidence: 99%

“…Additional immunologic cofactors may be involved such as interferon initiation or restoration immune syndrome under HAART or vaccination . Besides, several cases of granulomatous tattoo reactions under BRAF and MEK inhibitors have been reported . They illustrate that immunity modulation can lead to a localized reaction against tattoos: the tattoos are the target , but not the cause of the reaction.…”

Section: Discussionmentioning

confidence: 99%

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Tattoo‐associated uveitis with or without systemic sarcoidosis: a comparative review of the literature

Kluger

2018

Acad Dermatol Venereol

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Sarcoidosis is a systemic disease of unknown aetiology characterized by the presence of non-caseating epithelioid cell granulomas in multiple organs, mainly the lungs and the lymphatic system. It is also one of the leading cause of inflammatory eye diseases. For the past 70 years, sarcoidal granulomas on tattoos and permanent make-up have been documented. They can be the first and sometimes unique cutaneous manifestation of systemic sarcoidosis. A few cases of sarcoidosis with uveitis and granulomatous reactions within tattoos have been described. However, since the end 60s, a singular entity has been reported associating isolated uveitis with granulomatous cutaneous reaction restricted to tattoos in the notable absence of systemic sarcoidosis. It remains unclear whether this entity must be distinguished from sarcoidosis. This review summarizes the currently available data on this topic and compares cases of sarcoidosis with granulomatous tattoo reaction and uveitis to the cases without notable sarcoidosis. We propose the acronym TAGU (TAttoo Granulomas with Uveitis) as an exclusion diagnosis that emcompasses the patients for whom we fail to find any sarcoidosis or other causes after extensive investigation.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Tattoo‐associated uveitis with or without systemic sarcoidosis: a comparative review of the literature

Kluger

2018

Acad Dermatol Venereol

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“…To the best of our knowledge, only six cases of skin reaction to tattoos during BRAF and MEK inhibitor therapy, like with our patient, have been reported in the literature: three of them describe directly granulomatous findings at biopsy [21][22][23] and the other ones only mild lymphocytic infiltrations [24][25][26]. There are no cases reported in the literature of skin reactions to tattooing during alternative target therapies for melanoma such as Vemurafenib and Cobimetinib.…”

Section: Discussionmentioning

confidence: 53%

Tattoo-Associated Skin Reaction in a Melanoma Patient Receiving B-RAF and MEK Inhibitors: A Case Report with an Emphasis on Etiopathogenic and Histological Features

Baratta,

Cazzato,

Foti

et al. 2024

JCM

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Tattoo-associated cutaneous reactions have become quite frequent given the increasing percentage of tattooed subjects globally and also in Italy. On the other hand, the increasing use of target therapy is showing the ability of these drugs to affect the immune system and also cause adverse tattoo-related reactions. In this paper, we report a case of a 42-year-old patient with stage-IIID melanoma undergoing treatment with Dabrafenib and Trametinib. The patient reported erythema, oedema and scaling in areas of the body containing a black tattoo, and, conversely, no signs and/or symptoms in areas with tattoos of a different color. Histopathological and immunohistochemical features indicated a lympho-histiocytic reaction with a granulomatous morphology, mainly distributed around the vessels and hair adnexa. By discussing the cases reported in the literature prior to ours, we concluded and provided the possible indications of the pathogenesis.

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The suppressive effect of dabrafenib, a therapeutic agent for metastatic melanoma, in IgE-mediated allergic inflammation

Choi

Lee

Choi

et al. 2020

International Immunopharmacology

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Hypersensibilité retardée aux tatouages induite par un traitement combiné anti-BRAF/anti-MEK

Cited by 4 publications

References 21 publications

Tattoo‐associated uveitis with or without systemic sarcoidosis: a comparative review of the literature

Tattoo‐associated uveitis with or without systemic sarcoidosis: a comparative review of the literature

Tattoo-Associated Skin Reaction in a Melanoma Patient Receiving B-RAF and MEK Inhibitors: A Case Report with an Emphasis on Etiopathogenic and Histological Features

The suppressive effect of dabrafenib, a therapeutic agent for metastatic melanoma, in IgE-mediated allergic inflammation

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