Hypersensitivity Reactions to Corticosteroids

Allergic contact dermatitis to corticosteroids: experience of a referral clinic from 2014 to 2018

“…According to the literature, the main risk factors for ACD to corticosteroids are the presence of previous chronic dermatoses, use of corticosteroids without medical follow-up, and genetic susceptibility. 1 Corroborating these findings, the six patients had a history of irregular and prolonged use of topical corticosteroids, as well as previous dermatoses: psoriasis in two (33.3%), stasis dermatitis in two (33.3%), and chronic eczema of undefined etiology in two (33.3%).…”

“…However, there is little discussion regarding the role of corticosteroids as possible triggers of an allergic process. 1 , 2 …”

“…The frequency of ACD to corticosteroids varies from 0.5 to 5% in the literature. 1 , 3 In Brazil, there are no statistical data on the topic, which justifies the performance of the current study, which was approved by the Ethics Committee of the institution. (33471620.7.0000.5479).…”

Delayed hypersensitivity to topical and systemic corticosteroids

“…However, this classification does not seem to be useful for predicting SAD. Extensive diagnostic approaches are necessary, such as prick tests, intradermal testing, and challenge tests, for assessment of the individual sensitization/tolerance profile .…”

Guía para el diagnóstico, el tratamiento y la prevención del eccema de manos

“…El tratamiento durante más de 6 semanas debe ser excepcional y solo llevarse a cabo bajo supervisión médica 3 . Además, se deben considerar las reacciones de hipersensibilidad inmediatas y diferidas cuando se usan CT, que deben ser estudiadas mediante pruebas epicutáneas 70 . Por lo general, para tratar el EM se eligen los CT de alta potencia (valerato de betametasona al 0,05% o al 0,1% en crema, furoato de mometasona al 0,1% en crema) y la administración una vez al día es suficiente.…”