Hypertension and Cardiovascular Risk Profile in a Middle-Income Setting: The HELISUR Study

Diemer, Frederieke S.; Baldew, Se-Sergio; Haan, Yentl C.; Aartman, Jet Q; Karamat, Fares A.; Venrooij, Lenny M. W. Nahar-van; Montfrans, Gert A. van; Oehlers, G.P.; Brewster, Lizzy M.

doi:10.1093/ajh/hpx105

Cited by 10 publications

(13 citation statements)

References 15 publications

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“…The Suriname Healthy study and the Healthy Life in Suriname (HeliSur) study have shown that Hindustani and Creole people have high prevalence of CVD risk factors such as DM and HT rates, which is in line with the high prevalence found in our study. 23 , 28 , 29 HF admissions due to IHD were twice as high in patients of Asian descent compared to HF patients of African descent, whereas HHD was more prevalent in HF patients of African descent compared to patients of Asian descent. This is in line with studies, showing that atherosclerotic diseases and IHD are more prevalent in Asian and HHD in Africans.…”

Section: Resultsmentioning

confidence: 89%

“…21 CVD is the major cause of death (28%) and several studies on CVD risk factors prevalence in Suriname, have shown a high and rising prevalence of these risk factors. 22 , 23 , 24 , 25 , 26 , 27 The Suriname Health Study, for instance, demonstrated a prevalence of 26% for HT, 14% for DM and approximately 30% of people between 55 and 64 years of age with three or more CVD risk factors. 28 , 29 This high prevalence of risk factors may result in a high CVD and HF burden.…”

Section: Introductionmentioning

confidence: 99%

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Heart Failure Hospitalizations and Risk Factors among the Multi-Ethnic Population from a Middle Income Country: The Suriname Heart Failure Studies

Sairras

Baldew

Hilst

et al. 2021

Journal of the National Medical Association

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Introduction Heart failure (HF) is an emerging epidemic with poor disease outcomes and differences in its prevalence, etiology and management between and within world regions. Hypertension (HT) and ischemic heart disease (IHD) are the leading causes of HF. In Suriname, South-America, data on HF burden are lacking. The aim of this Suriname Heart Failure I (SUHF–I) study, is to assess baseline characteristics of HF admitted patients in order to set up the prospective interventional SUHF-II study to longitudinally determine the effectiveness of a comprehensive HF management program in HF patients. Methods A cross-sectional analysis was conducted of Thorax Center Paramaribo (TCP) discharge data from January 2013-December 2015. The analysis included all admissions with primary or secondary discharge of HF ICD-10 codes I50-I50.9 and I11.0 and the following variables: patient demographics (age, sex, and ethnicity), # of readmissions, risk factors (RF) for HF: HT, diabetes mellitus (DM), smoking, and left ventricle (LV) function. T-tests were used to analyze continuous variables and Chi-square test for categorical variables. Differences were considered statistically significant when a p-value <0.05 is obtained. Results 895 patients (1:1 sex ratio) with either a primary (80%) or secondary HF diagnosis were admitted. Female patients were significantly older (66.2 ± 14.8 years, p < 0.01) at first admission compared to male patients (63.5 ± 13.7 years) and the majority of admissions were of Hindustani and Creole descent. HT, DM and smoking were highly prevalent respectively 62.6%, 38.9 and 17.3%. There were 379 readmissions (29.1%) and 7% of all admissions were readmissions within 30 days and 16% were readmissions for 31-365 day. IHD is more prevalent in patients from Asian descendant (52.2%) compared to African descendant (11.7%). Whereas, HT (39.3%) is more prevalent in African descendants compared to Asian descendants (12.7%). There were no statistically significant differences in age, sex, ethnicity, LV function and RFs between single admitted and readmitted patients. Conclusion RF prevalence, ethnic differences and readmission rates in Surinamese HF patients are in line with reports from other Caribbean and Latin American countries. These results are the basis for the SUHF-II study which will aid in identifying the country specific and clinical factors for the successful development of a multidisciplinary HF management program.

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Section: Resultsmentioning

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Heart Failure Hospitalizations and Risk Factors among the Multi-Ethnic Population from a Middle Income Country: The Suriname Heart Failure Studies

Sairras

Baldew

Hilst

et al. 2021

Journal of the National Medical Association

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“…We recently reported the prevalence of hypertension, obesity, diabetes, and dyslipidemia in Paramaribo, Suriname: respectively 39.5%, 36.8%, 14.5%, and 40.9% . The sample size calculation was based on the lowest prevalence (ie, diabetes) and we calculated that at least 690 women were needed to assess a difference in these risk factors with α = .05 and 1‐β = .80 using multivariable logistic regression analysis with 10 other predictors.…”

Section: Methodsmentioning

confidence: 99%

The risk of hypertension and cardiovascular disease in women with uterine fibroids

Haan

Diemer

Woude

et al. 2018

J of Clinical Hypertension

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Women with fibroids have a notably high hypertension risk. However, adjusted data regarding other cardiovascular disease (CVD) risk factors are scarce. In this cross-sectional study, CVD risk factors, hemodynamic parameters, and asymptomatic organ damage were analyzed between women with uterine fibroids and controls in a multi-ethnic population. In total, 104 women with self-reported fibroids and 624 controls were included. Women with fibroids had significantly higher odds to have hypertension (OR 3.4; 95% CI 2.2-5.2), diabetes (1.7; 1.0-2.9), and hypercholesterolemia (1.8; 1.1-3.2). After adjustment for confounders, only the odds ratio for hypertension was significant (1.8; 1.1-3.1). Asymptomatic organ damage occurred significantly more often in women with fibroids (66.7%; 95% CI 55.8%-77.6% vs 42.9%; 38.0-47.8 in controls), especially in the younger age group (respectively 48.5%; 31.1%-65.9% vs 22.1%; 17.0-27.2). In this study, women with fibroids had a remarkably high hypertension risk compared to controls, with more asymptomatic organ damage, in particular young women.

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“…Suriname is a Caribbean nation with approximately 560,000 citizens who are mainly of African or Asian (South Asian, Indonesian, and Chinese) ancestry. More than 70% of the population lives in an urban setting [7–12]. The gross national income per capita (i.e.…”

Section: Methodsmentioning

confidence: 99%

“…Diseases of the circulatory system are the main cause of death [7, 10]. The Healthy Life in Suriname (HeliSur) study was the first major scientific study, conducted from 2014 to 2017 in a random sample of the urban population, designed to assess cardiovascular risk factors as well as asymptomatic and symptomatic target organ damage including CKD.…”

Section: Methodsmentioning

confidence: 99%

Chronic kidney disease and kidney health care status: the healthy life in Suriname (HeliSur) study

et al. 2018

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The high cardiovascular risk burden in low- and middle-income countries is expected to lead to an explosive increase in chronic kidney disease (CKD). However, population data on CKD from these countries are scarce. Therefore, we assessed kidney health in Suriname. In the Healthy Life in Suriname (HeliSur) study, a random sample of the adult population, we collected data with standardized questionnaires, physical examination, and blood and urine samples analysed in a central laboratory. Prevalent CKD was graded with KDIGO guidelines. In addition, we assessed national data on prevalent renal replacement therapy (RRT), estimated the future need for RRT, and evaluated national kidney health work force and policies. We include 1117 participants (2.0‰ of the population), 63% women, 40% of African ancestry and 43% of Asian ancestry, with a mean age of 42.2 (SE 0.4) years. Blood pressure is elevated in 72% of the participants, 26% have diabetes or prediabetes, and 78% are obese or overweight. The prevalence of CKD is 5.4%, and around 0.3% have kidney failure, translating to approximately 1500 patients nationally (2690 per million population, pmp), with currently 516 patients (920 pmp) on dialysis. Based on the participants from the random population sample in CKD stage G3 or G4, we estimate that 6750–10,750 pmp may develop kidney failure within the next 10 years. However, specialized kidney health workforce is currently very limited, and specific national or local policies for CKD management are lacking. Since the large majority of the general population has one or more risk factors for CKD including elevated blood pressure, urgent action is needed to strengthen kidney health care and prevent a catastrophic rise in need for RRT in the coming years.

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Hypertension and Cardiovascular Risk Profile in a Middle-Income Setting: The HELISUR Study

Cited by 10 publications

References 15 publications

Heart Failure Hospitalizations and Risk Factors among the Multi-Ethnic Population from a Middle Income Country: The Suriname Heart Failure Studies

Heart Failure Hospitalizations and Risk Factors among the Multi-Ethnic Population from a Middle Income Country: The Suriname Heart Failure Studies

The risk of hypertension and cardiovascular disease in women with uterine fibroids

Chronic kidney disease and kidney health care status: the healthy life in Suriname (HeliSur) study

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