Hypertension and menopause

Abstract

The climacteric period (menopause) is one of the most important periods in a woman's life, reflecting the natural extinction of the reproductive function. Current hormonal changes and developing menopausal disorders initiate the formation of pathological conditions that have a negative impact on both the health and expectancy of life and its quality. Cardiovascular diseases are one of the most common pathological conditions. Arterial hypertension (AH) is a key risk factor for the development of cardiovascular diseases, in different periods of menopause has various clinical and pathogenetic features that must be considered during treatment. Indapamide have pronounced antihypertensive effect, organprotective properties and metabolic neutrality. It is drug of choice for mono or combination therapy for women with hypertension during different periods of menopause. Effective antihypertensive and organprotective action, metabolic neutrality and safety of nitrendipine use allow us to recommend this drug for combination therapy of hypertension in women in distant menopause. The combination of indapamide and nitrendipine may be one of the most effective tools for hypertension treating in women in distant climacteric period.

Sex differences in the antihypertensive treatment and risk of uncontrolled hypertension in 5308 hypertensive patients in the United Arab Emirates

“…We know from observational studies that the increase in age would be associated with poor BP control [5,18,26]. Menopause is one of the factors that predispose women of this age group to hypertension [26–28]. Predisposing factors to the development of hypertension that affect post-menopausal women disproportionately include obesity, affecting up to 40% of menopaused women, and depression and anxiety [29–31].…”