Hypertension, fetal growth restriction and obstructive sleep apnoea in pregnancy

Yin, Tang; Williams, Neil C.; Burton, C.; Ong, Stephen; Loughna, Pamela; Britton, John; Thornton, Jim

doi:10.1016/j.ejogrb.2008.07.009

Cited by 41 publications

(41 citation statements)

References 15 publications

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“…However, that study did not report comorbidities or adjust for confounders such as diabetes, hypertension and gestational hypertensive disorders. Our study did not show a significant association with growth restriction and is consistent with other studies [13,17,29,48]. A limitation of most existing studies, including this study, relates to the lack of confirmation of gestational age by early gestation ultrasound in some subjects and the lack of longitudinal fetal growth data, leading to the possibility of missing a true effect.…”

Section: Neonatal Outcomessupporting

confidence: 78%

Pregnancy and fetal outcomes of symptoms of sleep-disordered breathing

Bourjeily

Raker²,

Chalhoub³

et al. 2010

Eur Respir J

208

230

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The physiological changes of pregnancy may predispose females to develop sleepdisordered breathing (SDB) or protect against it. Studies evaluating outcomes of SDB symptoms in pregnancy are scarce. The goal of this study was to evaluate the prevalence of SDB symptoms in pregnancy and their relationship with pregnancy and neonatal outcomes.A cross-sectional survey of randomly selected immediate postpartum females was performed using the multivariable apnoea prediction index. Record review, including demographics and medical history, was performed. Main outcome measures included pregnancy and neonatal outcomes.1,000 subjects were recruited. Mean¡SD age was 29.1¡6.1 yrs. Factors used in the regression analysis included age, body mass index, diabetes, chronic hypertension, multifetal gestations, smoking and renal disease. Snoring was present in 35.1% of subjects. Symptoms of SDB were associated with a higher likelihood of pregnancy-induced hypertension and pre-eclampsia (adjusted OR 2.3, 95% CI 1.4-4.0), gestational diabetes (adjusted OR 2.1, 95% CI 1.3-3.4) and unplanned Caesarean deliveries (adjusted OR 2.1, 95% CI 1.4-3.2) after multivariable regression analysis. Gasping may have been associated with a higher likelihood of preterm delivery, after adjusting for age and multifetal pregnancies (adjusted OR 1.8, 95% CI 1.1-3.2) but this association appeared to be mediated by pre-eclampsia.Symptoms of SDB are common in pregnancy and associated with a higher likelihood of gestational hypertensive disorders, gestational diabetes and unplanned Caesarean deliveries.

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Section: Neonatal Outcomessupporting

confidence: 78%

Pregnancy and fetal outcomes of symptoms of sleep-disordered breathing

Bourjeily

Raker²,

Chalhoub³

et al. 2010

Eur Respir J

208

230

View full text Add to dashboard Cite

show abstract

“…The few previous studies examining the link between maternal SDB and the delivery of SGA babies as a primary outcome have yielded mixed results. However, the majority of studies used symptom-based assessments of SDB,15 16 35 39 40 and the timing of ascertainment of symptoms during pregnancy and exact symptom definition of SDB varied significantly. Of the two studies that used PSG-based diagnoses of SDB, one was a retrospective cohort study23 that showed no association and the other, a large database study22 demonstrated a positive association.…”

Section: Discussionmentioning

confidence: 99%

Maternal sleep-disordered breathing and the risk of delivering small for gestational age infants: a prospective cohort study

Pamidi

Marc

Simoneau

et al. 2016

Thorax

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“…Berlin or Hawaii questionnaire, Epworth sleepiness scale). 31,34,35,37,42,44,46,48,49,88,90,91 The gold standard for the diagnosis of sleep disorders is polysomnography, in which the patient is studied and monitored continuously in a sleep laboratory. This modality consists of a comprehensive recording of biophysiologic parameters by electroencephalography, electrooculography, electromyography, electrocardiography, nasal and oral airflow as well as pulse oximetry.…”

Section: The Diagnosis Of Sleep Disordersmentioning

confidence: 99%