Hypertension the ‘Missed Modifiable Risk Factor’ for Diabetic Neuropathy: a Systematic Review

Sethi, Yashendra; Uniyal, Nidhi; Vora, Vidhi; Agarwal, Pratik; Murli, Hamsa; Joshi, Archi; Patel, Neil; Chopra, Hitesh; Hasabo, Elfatih A.; Kaka, Nirja

doi:10.1016/j.cpcardiol.2022.101581

Cited by 10 publications

(5 citation statements)

References 47 publications

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“…Other comorbidities seen in patients with peripheral neuropathy are hypertension and dyslipidemia. Similar with hyperglycemia, dyslipidemia and hypertension causes microvascular disorder due to chronic endothelial injury and dysfunction which results in nerve damage [ [36] , [37] , [38] , [39] ].…”

Section: Discussionmentioning

confidence: 99%

Factors correlating to decisions for prescribing pharmacological treatment and referrals in suspected peripheral neuropathy cases in chat consultation-based application

Prawiroharjo,

Anggraini,

Geraldi

et al. 2024

Heliyon

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Section: Discussionmentioning

confidence: 99%

Factors correlating to decisions for prescribing pharmacological treatment and referrals in suspected peripheral neuropathy cases in chat consultation-based application

Prawiroharjo,

Anggraini,

Geraldi

et al. 2024

Heliyon

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“…Since blood pressure regulation is clinically addressed for the prevention of distal symmetric polyneuropathy, hypertension can exacerbate poly-neuropathies in diabetes patients. [27,28] Smoking, alcohol Alcohol intake and smoking are also regarded as separate risk factors for DN. [4,5] In diabetics, a number of endogenous elements secreted by the liver, skeletal muscle, endothelium, and various other tissues are known to play a crucial role in preventing damage and preserving the homeostasis of the vasculature.…”

Section: Hypertensionmentioning

confidence: 99%

Recent Advances in Biomolecular Patho-Mechanistic Pathways behind the Development and Progression of Diabetic Neuropathy

Ratan,

Rajput,

Pareek

et al. 2024

Biomedicines

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Diabetic neuropathy (DN) is a neurodegenerative disorder that is primarily characterized by distal sensory loss, reduced mobility, and foot ulcers that may potentially lead to amputation. The multifaceted etiology of DN is linked to a range of inflammatory, vascular, metabolic, and other neurodegenerative factors. Chronic inflammation, endothelial dysfunction, and oxidative stress are the three basic biological changes that contribute to the development of DN. Although our understanding of the intricacies of DN has advanced significantly over the past decade, the distinctive mechanisms underlying the condition are still poorly understood, which may be the reason behind the lack of an effective treatment and cure for DN. The present study delivers a comprehensive understanding and highlights the potential role of the several pathways and molecular mechanisms underlying the etiopathogenesis of DN. Moreover, Schwann cells and satellite glial cells, as integral factors in the pathogenesis of DN, have been enlightened. This work will motivate allied research disciplines to gain a better understanding and analysis of the current state of the biomolecular mechanisms behind the pathogenesis of DN, which will be essential to effectively address every facet of DN, from prevention to treatment.

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“…Most diabetes patients have hypertension due to diabetes. Diabetics have a higher risk of cardiovascular disease, nephropathy, retinopathy, and neuropathy if they suffer from hypertension (Haq et al, 2019;Sethi et al, 2023).…”

Section: Introductionmentioning

confidence: 99%

Meta-Analysis of the Effects of Barberry Consumption on Blood Pressure in Non-Communicable Disease Patients

Adriani,

Adriana,

Hapsari

et al. 2024

ijsh

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This study delves into the potential benefits of barberry consumption on blood pressure in individuals with hypertension and its effects on various non-communicable diseases. Barberry was chosen for investigation due to its historical use in traditional medicine and emerging evidence suggesting its positive impact on health. Barberry contains bioactive compounds like berberine, which have been associated with cardiovascular health benefits such as lowering blood pressure and cholesterol levels. Given the rising prevalence of hypertension and other non-communicable diseases globally, understanding the potential therapeutic effects of barberry could offer novel preventive and therapeutic strategies. Through the systematic review and meta-analysis of relevant literature, this study aims to provide a comprehensive assessment of the efficacy of barberry in managing blood pressure and its implications for public health interventions targeting non-communicable diseases.

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Hypertension the ‘Missed Modifiable Risk Factor’ for Diabetic Neuropathy: a Systematic Review

Cited by 10 publications

References 47 publications

Factors correlating to decisions for prescribing pharmacological treatment and referrals in suspected peripheral neuropathy cases in chat consultation-based application

Factors correlating to decisions for prescribing pharmacological treatment and referrals in suspected peripheral neuropathy cases in chat consultation-based application

Recent Advances in Biomolecular Patho-Mechanistic Pathways behind the Development and Progression of Diabetic Neuropathy

Meta-Analysis of the Effects of Barberry Consumption on Blood Pressure in Non-Communicable Disease Patients

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