Hypertensive Disorders of Pregnancy

Bellomo, Gianni

doi:10.1007/978-3-319-59918-2_44

Cited by 1 publication

(3 citation statements)

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“…Higher incidence rates have been observed, such as 8.7% in a study from Canada [2]. Such wide variations are probably related to intrinsic characteristics of the populations studied and to the diagnostic criteria adopted [1].…”

Section: Introductionmentioning

confidence: 88%

“…Preeclampsia is an endothelial disorder unique to human pregnancy, with multiple organ involvement; especially kidney lesion, defined as "glomerular endotheliosis", represents a specific variant of thrombotic microangiopathy characterized by glomerular endothelial swelling with loss of endothelial fenestrae and occlusion of the capillary lumens; the lesion, however, is not specific of pre-eclampsia, as it was found in women with normal pregnancy as well as in both non-proteinuric and proteinuric hypertension and is consequently not, as earlier believed, pathognomonic of preeclampsia [1,4,5].…”

Section: Introductionmentioning

confidence: 97%

“…Preeclampsia, formerly known as toxemia of pregnancy, can be defined as new onset hypertension, after the 20 th week of gestation, associated with proteinuria and/or other signs of end-organ damage. The term eclampsia refers to the occurrence of seizures that cannot be attributed to other causes in a woman with pre-eclampsia [1].…”

Section: Introductionmentioning

confidence: 99%

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Doppler Indices "UAI" Enfluence by MgSO4 and Fetal Circulation in Cases of Severe Pre-Eclampsia

EMARA

2022

The Medical Journal of Cairo University

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Background: Preeclampsia, is development of new onset hypertension with proteinuria and leads to endothelial disorder with multiple organ involvement in pregnant women. Severe pre-eclampsia is characterized by the progressive deterioration of both mothers and fetus. The use of MgSO 4 is beneficial in severe PE. Aim of Study:This study aimed to assess the effect of Magnesium sulfate injection on Doppler indices and fetal circulation in cases of severe pre-eclampsia. Patients and Methods:This was a prospective comparative study conducted on 50 pregnant female with severe preeclampsia, selected from the Obstetrics and Gynecology Department of Damanhour Teaching Hospital during the period from Jan 2019 to Dec 2020 and were classified into group (A) and (B) each included 25 women (A) treated by ordinary management with MgSO 4 (I.V) and (B) with ordinary treatment of preeclampsia only. Doppler is used to assess the UA for follow-up.Data were fed to the computer using IBM SPSS software package version 20.0.Results: Our results revealed a non-significant statistical difference between both groups regarding demographic data of women, investigations done except AST and ALT there was a significant elevation in group B; also, there was significant decrease in UAI, UARI and systolic diastolic ratio of UA.In our study there was no difference between both groups regarding post-therapy complication either fetal or maternal. Conclusion:We can conclude that MgSO 4 when used decreases the incidence of complications in severe PE as well as reduces the uterine artery indices with beneficial effect on fetus.

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Section: Introductionmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 97%