Hyperthyroïdie et cancer du sein : y a-t-il une association ?

Cordel, E.; Reix, Nathalie; Molière, Sébastien; Mathelin, Carole

doi:10.1016/j.gofs.2018.01.010

Cited by 6 publications

(3 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Epidemiological studies have reported an increased risk of breast cancer in women with hyperthyroidism. [ 8 , 9 ] Gynecomastia and breast necrosis have been noted in patients with hyperthyroidism. [ 10 , 11 ] In our case, biopsy specimens of the bilateral breast showed no sign of malignant involvement or necrosis.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Bilateral breast myxedema caused by Graves’ disease and responsive to multipoint subcutaneous injection of long-acting glucocorticoid

Jiang

Luo

et al. 2021

Medicine

View full text Add to dashboard Cite

Rationale: With the absence of ophthalmopathy, thyroid dermopathy especially lesions at atypical locations is a very rare presentation. We herein report an original case of bilateral breast myxedema caused by Grave's disease. Patient concerns: A 21-year-old unmarried woman presented with a 4-month history of Grave's disease and a 1-month history of progressive bilateral breast enlargement. She had symmetrical bilateral breast enlargement with redness and nonpitting thickening of the skin, diffusely enlarged thyroid glands, and no exophthalmos. Diagnosis: Ultrasonography, magnetic resonance imaging scan, and skin biopsy confirmed the diagnosis of bilateral breast myxedema. Interventions: The patient was treated with multipoint subcutaneous injections of triamcinolone acetonide in each breast every month. Outcomes: The bilateral breast returned approximately to its normal size after therapy for 6 months. Conclusions: Our case illustrates that multipoint subcutaneous injection of glucocorticoids is beneficial for bilateral breast myxedema.

show abstract

Section: Discussionmentioning

confidence: 99%

“…However, bilateral breast myxedema has never been reported in association with thyroid disease. Epidemiological studies have reported an increased risk of breast cancer in women with hyperthyroidism [8,9] . Gynecomastia and breast necrosis have been noted in patients with hyperthyroidism [10,11] .…”

Section: Discussionmentioning

confidence: 99%

Bilateral breast myxedema caused by Graves’ disease and responsive to multipoint subcutaneous injection of long-acting glucocorticoid

Jiang

Luo

et al. 2021

Medicine

View full text Add to dashboard Cite

show abstract

“…Because breast cancer occurs more frequently in women, most researchers have focused on the relationship between sex hormone and breast cancer. However, recent findings have shown that other hormones can also influence breast cancer progression, such as thyroxine [ 59 ] and adrenaline [ 60 ].…”

Section: Cell Communication Between the Local Breast Cancer Microenvironment And The Internal And External Environmentsmentioning

confidence: 99%

Using dynamic cell communication improves treatment strategies of breast cancer

Liu

Hu²,

Yun

et al. 2021

Cancer Cell Int

View full text Add to dashboard Cite

Several insights from the clinical treatment of breast cancer patients have revealed that only a portion of patients achieve the expected curative effect after traditional targeted therapy, that surgical treatment may promote the development of cancer metastasis, and that the optimal combination of neoadjuvant chemotherapy and traditional treatment is not clear. Therefore, a more precise classification of breast cancer and selection of treatment methods should be undertaken to improve the efficacy of clinical treatment. In the clinical treatment of breast cancer, cell communication molecules are often selected as therapeutic targets. However, various cell communications are not static. Their dynamic changes are related to communicating cells, communicating molecules, and various intertwined internal and external environmental factors. Understanding the dynamic microenvironment can help us improve therapeutic efficacy and provide new ways to more accurately determine the cancer status. Therefore, this review describes multiple types of cellular communication in the breast cancer microenvironment and incorporates internal and external environmental factors as variable signaling factors in cell communication. Using dynamic and developmental concepts, we summarize the functional changes in signaling molecules and cells to aid in the diagnosis and treatment of breast cancer.

show abstract

The relationship between breast cancer and thyroid autoimmune disorders in southeast Iran: A case-control study

Nosratzehi,

Hashemi,

Payandeh

et al. 2024

Endocrine Regulations

View full text Add to dashboard Cite

Objective. To better understand the role of thyroid hormones in regulating the growth of breast epithelial cells and the estrogen-like effects of these hormones, the present study was conducted to investigate the relationship between breast cancer and thyroid autoimmune disorders in southeast Iran women. Methods. In this case-control study, in the case group, all newly diagnosed breast cancer patients referred to the oncology clinics in Zahedan city in years 2021‒2022 were studied. The number of participants in each group was represented by 40 breast cancer patients. The control group was represented by women without breast cancer. The sampling method was simple or available using the nonprobability method. The presence or absence of thyroid dysfunction was checked using thyroid-stimulating hormone (TSH), free thyroxin (FT4), free triiodothyronine (FT3), anti-thyroid peroxidase (TPO), and anti-thyroglobulin (Tg) tests. Results. The mean age of participants was 47±11 years. The risk of subclinical hyperthyroidism was higher in subjects with breast cancer and about 8 times higher than in the healthy ones (OR=8.27). According to the value of OR=1, the risk of developing autoimmune thyroid disease was the same in individuals with breast cancer as in healthy individuals. The odds ratio of hypothyroidism could not be calculated because the value in the control group was zero. Conclusion. The results of this study show that there are abnormal characteristics of the thyroid gland in breast cancer patients compared to the control group. The incidence of subclinical hyperthyroidism was significantly increased in the breast cancer patients. However, there was no difference in the incidence of autoimmune thyroid disease between the two groups.

show abstract

Hyperthyroïdie et cancer du sein : y a-t-il une association ?

Cited by 6 publications

References 38 publications

Bilateral breast myxedema caused by Graves’ disease and responsive to multipoint subcutaneous injection of long-acting glucocorticoid

Bilateral breast myxedema caused by Graves’ disease and responsive to multipoint subcutaneous injection of long-acting glucocorticoid

Using dynamic cell communication improves treatment strategies of breast cancer

The relationship between breast cancer and thyroid autoimmune disorders in southeast Iran: A case-control study

Contact Info

Product

Resources

About