Hypertrophic Obstructive Cardiomyopathy (HOCM)

Kern, Morton J.

doi:10.1002/9781119095651.ch11

Cited by 2 publications

(3 citation statements)

References 47 publications

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“…проба на Валсалва, пост-екстрасистолно усилване на миокардната контракцията). Това е изключително важно за пациентите, при които симптоматиката се появява при физическо усилие и при тези, имащи нисък градиент на ЛКИТ обструкция в покой [13].…”

Section: инвазивната хемодинамична оценка при хкмп има няколко съществени предимстваunclassified

“…При измерване на ЛК налягания липсата на градиент между ЛК и аортата изключва наличието на обструкция в покой. Най-точният метод за оценка на ЛК обструкция е чрез използване на транссептален подход с балонен катетър, позициониран в ЛКИТ и "pigtail" катетър в асцендентната аорта за едновременно измерване на градиента [13]. В ежедневната практика изпълнението на този метод е трудно и свързано с усложняване на процедурата.…”

Section: инвазивната хемодинамична оценка при хкмп има няколко съществени предимстваunclassified

“…Сърдечната честота и периферното съдово съпротивление се повишават в края на пробата. Основният ефект на този прийом се изразява в намаляване на ЛК пълнене и преднатоварването [13].…”

Section: механизми за провокация на градиент в лкитunclassified

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Invasive hemodynamic assessment of patients with cardiomyopathies

Shumkova¹,

Karamfiloff²,

Ivanova³

et al. 2021

Bulgarian Cardiology

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Invasive hemodynamic assessment of cardiac diseases has become an important diagnostic tool in recent decades. Non-invasive methods are the main techniques used to assess cardiac function, due to their wider availability. Cardiac catheterization is useful when there are diagnostic problems that cannot be solved with routine methods. Cardiac catheterization should be individualized according to the specific problems of the patient and based on the results from non-invasive methods. Invasive diagnostics is used in the assessment of patients with various cardiovascular diseases, including cardiomyopathies. In this review, we consider the role of cardiac catheterization, its advantages and disadvantages as part of the overall assessment of patients with cardiomyopathies.  

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Section: инвазивната хемодинамична оценка при хкмп има няколко съществени предимстваunclassified

Section: механизми за провокация на градиент в лкитunclassified

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Invasive hemodynamic assessment of patients with cardiomyopathies

Shumkova¹,

Karamfiloff²,

Ivanova³

et al. 2021

Bulgarian Cardiology

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The Role of Alcohol Ablation Therapy in Hypertrophic Obstructive Cardiomyopathy Management

2024

IJCCD

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Objectives: The following study aims to investigate alcohol septal ablation’s (ASA) role in hypertrophic obstructive cardiomyopathy (HOCM) management, focusing on in-hospital outcomes, efficacy in reducing left ventricular outflow tract (LVOT) obstruction, and safety profiles. Methods: The study, conducted at the Institute of Cardiology, National Hospital of Sri Lanka, included a total of nine HOCM patients. Participants with exercise-induced symptoms, dyspnea/angina, and specific ventricular gradients were included; unidentified septal branches led to exclusion. Diagnostic assessments, including electrocardiogram, contrast echocardiography, and cardiac catheterization, confirmed HOCM. ASA procedures involved careful target septal branch selection, alcohol injection, and post-procedure care with temporary pacemaker monitoring. Results: The study population (N=9) comprised seven males and two females, with a mean age of 40. Pre- and post-ablation measurements showed 78% reduction in LVOT gradient. Immediate complications included chest pain (100%), while 22.2% developed complete heart block. Notably, no mortality occurred during the study. Conclusion: ASA proved safe and effective in managing HOCM, with significant mean reduction in post-ablation LVOT gradient (78%). Complications were generally minor, emphasizing ASA’s viability for symptomatic HOCM patients. While acknowledging the absence of randomized controlled trials comparing ASA with alternative techniques, this study contributes valuable insights to guide collaborative treatment decisions by specialists.

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Hypertrophic Obstructive Cardiomyopathy (HOCM)

Cited by 2 publications

References 47 publications

Invasive hemodynamic assessment of patients with cardiomyopathies

Invasive hemodynamic assessment of patients with cardiomyopathies

The Role of Alcohol Ablation Therapy in Hypertrophic Obstructive Cardiomyopathy Management

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