Hypertrophische Osteoarthropathie und Thrombozytopenie bei Bronchialkarzinom

Abstract

Hypertrophic osteoarthropathy is characterized by the combination of clubbing, arthropathy and periostitis. This paraneoplasia may be the presenting manifestation of occult malignancy. The diagnosis of hypertrophic osteoarthropathy should cause an intensive search of cancer. Further associated diseases are discussed.

Characteristics and survival of 26 patients with paraneoplastic arthritis

“…These observations suggest that arthritis might be an early manifestation of HOA and usually precede radiographic signs of periostitis. For patients with HOA, lung cancer was the most common underlying neoplasia (5 of 6; 83.3%) and this percentage is similar to those reported by other groups 16 17. Paraneoplastic arthritis is usually described as refractory to NSAIDs and steroids.…”

Trommelschlägelfinger und Dysphagie einer 38-jährigen Patientin

“…Die hypertrophe Osteoarthropathie ist eine typische Paraneoplasie pulmonaler Erkrankungen [3,4,7,15,18]. Sich schnell entwickelnde Trommelschlägelfinger [8] sowie das radiologische Bild der periostalen Hypertrophie sind Kennzeichen dieser Diagnose [16].…”