Hyperuricemia as a Predictor of Perinatal Outcomes in Pregnancy Induced Hypertension

Khalil, Shaimaa Sobhy Hamed; Elshourbagy, S; Hamad, Said Mohamed; Zeid, Essmat Hamdy Abo

doi:10.17140/goroj-5-147

Cited by 1 publication

(1 citation statement)

References 18 publications

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“…Hamed Khalil and colleagues in their study, “Hyperuricemia as a predictor of perinatal outcomes in pregnancy induced hypertension,” discovered that the link between harmful prenatal outcomes and high blood uric acid levels and pregnancy problems was direct. 20 …”

Section: Discussionmentioning

confidence: 99%

Elevated uric acid in gestational diabetes and its risk on pregnancy outcomes

Ahmed,

Saad,

Abbas

et al. 2024

SAGE Open Medicine

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Background: Over the past few years, gestational diabetes mellitus has become more common. According to earlier research, gestational diabetes mellitus is linked to higher uric acid levels, and gestational hyperuricemia is linked to poor maternal and neonatal outcomes. Aim and objectives: To assess the influence of elevated uric acid >5 mg/dl on pregnancy outcomes such as neonatal weight, respiratory distress, preterm delivery, neonatal intensive care unit admission, premature membrane rupture, oligohydramnios, cesarean section, and intensive care admission for mothers. Setting and methods: It is a prospective cohort study, carried out at obstetric/family medicine outpatient clinics, Cairo University Hospitals on 221 pregnant females with gestational diabetes mellitus in their third trimester of pregnancy, selected by random sampling, performed structured interviews, and tested for serum uric acid level and were separated into two groups, those with elevated uric acid >5 mg/dl (121) and those without elevated uric acid ⩽5 mg/dl (100) patients and then followed up until delivery in Cairo University Hospitals for collecting pregnancy outcome data. Results: There were statistically significant differences between the antepartum uric acid and neonatal complications, maternal complications, preterm, macrosomia, neonatal intensive care unit admission, premature rupture of membranes, oligohydramnios, and cesarean section between both groups. Conclusions: This study showed that elevated serum uric acid >5 mg/dl can predict the incidence of maternal and neonatal problems in gestational diabetes mellitus including preterm, macrosomia, neonatal intensive care unit admission, premature rupture of membranes, oligohydramnios, and cesarean section.

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Section: Discussionmentioning

confidence: 99%