2018
DOI: 10.1088/1361-6560/aaee24
|View full text |Cite
|
Sign up to set email alerts
|

Hypo-fractionated boost in locally advanced non-small cell lung cancer: temporal distribution of boost fractions

Abstract: To propose new schemas for radiation boosting of primary tumors, in locally advanced non-small cell lung cancers (NSCLC), in conjunction with standard chemoradiotherapy. To investigate the effect of temporal distributions of the boost fractions on tumor control. NSCLC cases, previously treated with 60 Gy in 30 fractions, were retrospectively planned by adding a radiation boost (25 Gy in 5 fractions) to the primary tumor. Several integrated and sequential boosting schedules were considered. Biological doses wer… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2020
2020
2021
2021

Publication Types

Select...
3
1

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(2 citation statements)
references
References 49 publications
0
2
0
Order By: Relevance
“…Definitive radiotherapy combined with chemotherapy remains the main part of treatment for patients with unresectable locally advanced non-small cell lung cancer (LANS CLC) [1,2]. Hypofractionated radiotherapy (HRT) has been demonstrated as an effective approach for dose escalation [3,4]. The use of HRT is still challenging due to the close distance of target and organs at risk (OAR) in LANSCLC.…”
Section: Backgorundmentioning
confidence: 99%
“…Definitive radiotherapy combined with chemotherapy remains the main part of treatment for patients with unresectable locally advanced non-small cell lung cancer (LANS CLC) [1,2]. Hypofractionated radiotherapy (HRT) has been demonstrated as an effective approach for dose escalation [3,4]. The use of HRT is still challenging due to the close distance of target and organs at risk (OAR) in LANSCLC.…”
Section: Backgorundmentioning
confidence: 99%
“…De nitive radiotherapy combined with chemotherapy remains the main part of treatment for patients with unresectable locally advanced non-small cell lung cancer (LANSCLC) [1,2]. Hypofractionated radiotherapy (HRT) has been demonstrated as an effective approach for dose escalation [3,4]. The use of HRT is still challenging due to the close distance of target and organs at risk (OAR) in LANSCLC.…”
Section: Introductionmentioning
confidence: 99%