Hypocholesterolaemic effect of yoghurt containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536

Abstract

The effect of a yoghurt supplement containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536 on plasma lipids, lipid peroxidation and the faecal excretion of bile acids was examined in rats fed a cholesterol-enriched diet. After 8 weeks, the rats in the positive control (PC) group who were fed the cholesterol-enriched diet showed significant increases in plasma total cholesterol (TC), low-density lipoprotein (LDL) cholesterol, and malondialdehyde (MDA). However, groups fed a cholesterol-enriched diet supplemented with yoghurt containing B. pseudocatenulatum G4 or B. longum BB536 had significantly lower plasma TC, LDL-C, very-low-density lipoprotein (VLDL) cholesterol, and MDA than had the PC group after 8 weeks of treatment. In addition, faecal excretion of bile acids was markedly increased in the rats fed the yoghurt containing B. pseudocatenulatum G4 or B. longum BB536 as compared to the PC and NC groups.

Effects of Polysaccharides from Mango’ Peel on Physiochemical and Sensory Properties of Non-Fat Yoghurts

“…Yoghurt was prepared according to method described by Al-Sheraji et al [15] with some modifications. Skim milk powder instant (NZMP, Fonterra, Auckland, New Zealand) was weighed, dissolved in water to constitute 12.00% skim milk (w/v) and divided into five experimental lots; one lot was fortified with 1.5 g L -1 polysaccharides (T1), the second lot with 1.0 g L -1 polysaccharides (T2), the third lot with 0.50 g L -1 polysaccharides (T3), the fourth lot with 1.5 g L -1 CMC (T4) and the fifth lot with 30 g L -1 Skim milk powder (T5).…”

Mathematically modelling the dynamics of cholesterol metabolism and ageing

“…This could be one cause of the increase in LDL-C with age. Interestingly, supplementation with probiotic strains in elderly rodent populations has been shown to reduce LDL-C levels (Al-Sheraji et al, 2012) as well as improve gut health (Tuohy et al, 2003) and increase immunity in human subjects (Moro-Garcia et al, 2013). Mutations in the gene coding for CETP have also been linked to healthy ageing.…”

The genome of Bifidobacterium pseudocatenulatum IPLA 36007, a human intestinal strain with isoflavone-activation activity

“…Molecular analyses have shown that members of the Bifidobacterium catenulatum group (which includes B. catenulatum and B. pseudocatenulatum ) are abundant in fecal samples from adult humans [2,3]. B. pseudocatenulatum strains have a number of probiotic properties, such as the possession of antinutrient-degrading enzymes [4], the ability to bind mutagenic aromatic amines [5], and the capacity to reduce cholesterol levels [6]. However, compared to other bifidobacterial species, the genome of B. pseudocatenulatum has been very little explored.…”