This study examined the relationship of depression to the sixteen scales constituting the Sixteen Personality Factor Questionnaire (16PF) by samples of elderly found in retirement communities and private residences. Scale two of the MMPI and the Geriatric Depression Scale (GDS) served as measures of depression in the prediction of the 16 PF scores. From the one hundred and two subjects who participated in the investigation, a multiple regression analysis indicated that depression scores were negatively related to Factor C (Ego Strength), Factor E (Dominance), Factor F (Impulsivity), Factor H (Boldness), and Factor Q3 (Ability to Bind Anxiety). Results were interpreted as indicating that geriatric-depression could be best conceptualized as a depressive-somatic phenomenon, the onset, severity, and longevity of which depended upon three distinct factors: (1) personality predispositions, (2) health factors, and (3) demographic factors.