2008
DOI: 10.1007/s11102-008-0142-2
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Hypogonadotropic hypogonadism: a consequence of Chiari-I malformation

Abstract: Chronic hydrocephalus, most commonly the result of aqueduct stenosis, is associated with both primary and secondary amenorrhea. Only six cases of secondary amenorrhea have been reported to date. We describe a women with cystic fibrosis who presented with secondary amenorrhea as a consequence of Chiari-I malformation and resultant hydrocephalus. The biochemical picture was characterized by hypogonadotropic hypogonadism. Resolution of the amenorrhea was observed to occur following 3rd ventriculostomy.

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“…Hypothalamohypophysial impairment of the different neuroendocrine axes due to normal-pressure hydrocephalus has been reported by Kumar et al [16] and Barber and Garvan [17]. …”
Section: Discussionmentioning
confidence: 97%
“…Hypothalamohypophysial impairment of the different neuroendocrine axes due to normal-pressure hydrocephalus has been reported by Kumar et al [16] and Barber and Garvan [17]. …”
Section: Discussionmentioning
confidence: 97%