Hypokalemic paralysis due to primary sjögren syndrome: Literature review

Rissardo, Jamir Pitton; Caprara, Ana Letícia Fornari

doi:10.4103/injms.injms_135_19

Cited by 4 publications

(4 citation statements)

References 22 publications

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“…The use of steroid reduces the relapse rate in Sjogren syndrome. 9 Our case report has one the rare presentation of Sjögren's syndrome presenting with acute flaccid paralysis. The limitation of the case report was that we couldn't perform labial salivary gland biopsy, ocular staining and sialography in this patient.…”

Section: Discussionmentioning

confidence: 82%

Acute flaccid Paralysis as first presentation of Primary Sjogren’s Syndrome: A case report from Nepal

et al. 2021

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Sjögren’s syndrome is an autoimmune disease with glandular and extra-glandular involvement. The common neurological manifestation of Sjögren’s syndrome are peripheral neuropathy, anterior horn cell disease, transverse myelitis and aseptic meningitis. However, Sjögren’s syndrome presenting with acute flaccid paralysis is rare phenomenon. We report a case of a 35-year-old woman who presented with acute flaccid paralysis with respiratory failure who was later diagnosed as Primary Sjogren’s syndrome.

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Section: Discussionmentioning

confidence: 82%

Acute flaccid Paralysis as first presentation of Primary Sjogren’s Syndrome: A case report from Nepal

et al. 2021

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“…Some medications can cause movement abnormalities that are not classified as DIMDs, such as serotonin syndrome, which can occur with certain antidepressants and other drugs [112]. Another possible differential diagnosis is electrolyte abnormalities [113], such as hypokalemic paralysis [114] or copper deficiency [115]. However, one should always consider stroke [116], for which imaging can help differentiate between peripheral and central causes.…”

Section: Differential Diagnosismentioning

confidence: 99%

Understanding Drug-Induced Movement Disorders: Causes, Symptoms, and Treatment

R. Santos

2024

Preprint

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Drug-induced movement disorders (DIMDs) are a group of neurological conditions caused by the use of certain medications. These disorders can significantly impact a person's quality of life and are essential to recognize and manage. This article provides an overview of the causes, symptoms, and treatment of DIMDs. DIMDs can manifest in various forms, including parkinsonism, tardive dyskinesia, dystonia, and akathisia. They are most commonly associated with medications such as neuroleptics, antidepressants, antipsychotics, antiemetics, and anticonvulsants. Risk factors for developing DIMDs include age, genetics, duration of medication use, and dose of medication. Symptoms of DIMDs can range from mild to severe and may include tremors, rigidity, bradykinesia, and involuntary movements. These symptoms can significantly impact a person's ability to perform daily activities and lead to social isolation and decreased quality of life. DIMD diagnoses are based on clinical evaluation, including a thorough medical history and physical examination. Imaging studies such as MRI or CT scans may also be used to rule out other possible causes of symptoms. Treatment of DIMDs involves the withdrawal of the offending medication if possible. Pharmacological treatments such as anticholinergic drugs, benzodiazepines, and dopamine agonists may also be used to manage symptoms. Non-pharmacological treatments such as physical, occupational, and speech therapy can also be beneficial. DIMDs are necessary neurological conditions that can significantly impact a person's quality of life. Early recognition and management of these disorders are essential for optimizing outcomes. Further research is needed to understand the underlying mechanisms of DIMDs better and to develop more effective treatments.

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“…Sjögren's syndrome is an autoimmune disorder that primarily affects the exocrine glands, leading to symptoms such as dry eyes and mouth [151]. While Sjögren's syndrome primarily targets the glands, it is essential to note that it is a systemic autoimmune condition that can affect various organs and tissues in the body [152].…”

Section: Sjögren's Syndromementioning

confidence: 99%

A Literature Review of Movement Disorder Associated with Medications and Systemic Diseases

Pitton Rissardo,

Fornari Caprara

2024

Preprint

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Movement disorders can be associated with various drugs and systemic diseases, posing diagnostic challenges for clinicians. This review explores the spectrum of movement disorders associated with pharmacological agents and medical conditions. Drug-induced movement disorders encompass a broad range of conditions resulting from exposure to medications that affect several neurotransmitters. Neuroleptic medications can lead to tardive dyskinesia, characterized by involuntary, repetitive movements. Antipsychotics and antiemetics, including metoclopramide, may induce acute dystonic reactions. Other drugs, such as dopamine receptor-blocking agents, can contribute to drug-induced parkinsonism. Beyond medications, movement disorders can also arise secondary to systemic diseases. Metabolic disorders like Wilson's disease, characterized by copper accumulation, may manifest as chorea or dystonia. Inflammatory conditions such as rheumatoid arthritis and systemic lupus erythematosus can result in secondary movement disorders due to autoimmune-mediated processes affecting the central nervous system. Movement disorders linked to drugs or systemic diseases often necessitate a thorough clinical evaluation, including detailed medication histories and comprehensive systemic assessments. Neuroimaging, laboratory investigations, and, in some cases, cerebrospinal fluid analyses and electrodiagnostic studies help in establishing accurate diagnoses. Management involves addressing the underlying cause, modifying medications, and employing symptomatic treatments.

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Hypokalemic paralysis due to primary sjögren syndrome: Literature review

Cited by 4 publications

References 22 publications

Acute flaccid Paralysis as first presentation of Primary Sjogren’s Syndrome: A case report from Nepal

Acute flaccid Paralysis as first presentation of Primary Sjogren’s Syndrome: A case report from Nepal

Understanding Drug-Induced Movement Disorders: Causes, Symptoms, and Treatment

A Literature Review of Movement Disorder Associated with Medications and Systemic Diseases

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