Hypokalemic Rhabdomyolysis Induced Acute Renal Failure As A Presentation Of Coeliac Disease

Abstract

Adult coeliac disease commonly presents without classical symptoms as chronic diarrhea and weight loss. We describe the case of a 31-year-old woman with persistent life-threatening hypokalemia, acute renal failure, and acute quadriplegia due to diarrhea that had continued for one month. Although there are cases of coeliac disease diagnosed with hypokalemic rhabdomyolysis in the literature, none of the cases developed acute renal failure. This is the first case in the literature diagnosed with acute renal failure due to hypokalemic rhabdomyolysis as a presentation of coeliac disease. In acute renal failure cases that present with hypokalemic rhabdomyolysis due to severe diarrhea, coeliac disease should be considered as a differential diagnosis despite the negative antigliadin IgA antibody.

Celiac Disease Complicated by Rhabdomyolysis

“…Chronic diarrhea may cause hypokalemia as a complication. Although extremely rare, CD patients may develop intercurrent rhabdomyolysis with hypokalemia (16)(17)(18)(19)(20)(21)(22)(23)(24). We herein report an extremely rare case of rhabdomyolysis that occurred following hypokalemia due to chronic diarrhea.…”