Hypolipidemic action of homeopathic drug Aesculus hippocasteneum in cholesterol fed rats

Mathur, Prashant; Sankhla, Aarti; Dashora, P. K.

doi:10.1007/bf02886670

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…Formation of dimeric species of Ce(IV) has been reported by a number of workers in sulfuric, nitric [16,20] and perchloric acids [21], while the existence of a trimeric cerium species has been reported in acetic acid medium [22]. In a number of studies, it has been reported that the first-order rate constant decreases with increasing cerium(IV) concentrations due to the formation of dimeric species [23][24][25]. The retarding trend shown by the oxidant at higher concentrations may also be due to the formation of a complex between the oxidant and sulfuric acid, according to the following equilibria;…”

Section: Mechanismmentioning

confidence: 95%

Oxidation of butane-1,3-, butane-1,4-, 2-methyl pentane-2,4- and 3-methyl pentane-2,4-diols by cerium(IV) in aqueous acidic medium catalyzed by rhodium(III)

Tandon

Khanam

Yadav

et al. 2011

Transition Met Chem

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The oxidation kinetics of butane-1,3-diol, butane-1,4-diol, 2-methyl pentane-2,4-diol and 3-methyl pentane-2,4-diol with cerium(IV) catalyzed by rhodium(III) in aqueous sulfuric acid showed a peculiar nature with respect to the variation in oxidant concentration, such that the reaction follows first-order kinetics in [Ce(IV)] at low [Ce(IV)] and then reaches a maximum with increasing [Ce(IV)], beyond which further increase in the oxidant concentration retards the rate. The rate shows direct proportionality with respect to [diol] at low concentrations, becoming independent of [diol] at higher concentrations. The rate is first order in catalyst. Retarding effects are observed when [H ? ] and [Ce(III)] are increased, while [Cl -] and hence ionic strength have a positive effect on the rate. Spectroscopic studies confirmed that the primary hydroxyl groups in butane-1,3-diol and butane-1,4-diol resulted in the formation of 3-hydroxy butanal and 4-hydroxy butanal, respectively. In the case of oxidation of the secondary hydroxyl groups in 2-methyl pentane-2,4-diol and 3-methyl pentane-2,4-diol, the products of oxidation were 4-hydroxy-4-methyl pentan-2-one and 4-hydroxy-3-methyl pentan-2-one, respectively.

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