Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice

Abstract

In this study, the hepatoprotective and hypolipidemic effects of high-polydextrose snack food on Swiss albino mice were investigated. e mice were randomly divided into three groups: control diet, high-fat diet, and high-fat and fiber diet groups. Addition of high-polydextrose snack to the high-fat diet resulted in significant reduction in the liver weight, the accumulation of lipid droplets in liver, and the liver damage of hyperlipidemic mice in comparison with the high-fat diet. e high-polydextrose snack also decreased the content of total triglyceride, cholesterol, and low-density lipoprotein cholesterol as well as the alanine aminotransferase and aspartate aminotransferase activities in the mice serum. In addition, the high-polydextrose snack significantly increased the high-density lipoprotein cholesterol content of the hyperlipidemic mice. Consequently, use of highpolydextrose snack generated hepatoprotective and hypolipidemic effects on hyperlipidemic mice.

Hubungan asupan makan dan lingkar pinggang dengan status gizi pada lansia di Panti Wreda Rindang Asih I

“…Lingkar pinggang merupakan prediktor resistensi insulin dan hipertensi. Resistensi insulin berperan besar dalam terjadinya sindrom metabolik (Yang et al, 2020).…”