Hypolipidemic Effect of Triphala in Experimentally Induced Hypercholesteremic Rats

Saravanan, S.; Srikumar, Ramakrishnan; Manikandan, S.; Parthasarathy, Narayanaperumal Jeya; Devi, Rathinasamy Sheela

doi:10.1248/yakushi.127.385

Cited by 73 publications

(55 citation statements)

References 17 publications

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“…Triphala recipe possesses many biological activities including antimutagenic (Kaur et al, 2002), radioprotective (Sandhya et al, 2006a), hypocholesterolaemic (Saravanan et al, 2007), immunomodulatory (Srikumar et al, 2005), anticancer (Deep et Sandhya et al, 2006b), and anti-oxidant activities (Naik et al, 2005). Moreover, this recipe has an anti-inflammatory activity on adjuvant-induced arthritis in mice (Rasool and Sabina, 2007).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of anti-inflammatory and antinociceptive activity of Triphala recipe

Sireeratawong¹,

Jaijoy²,

Soonthornchareonnon³

2013

Afr. J. Trad. Compl. Alt. Med.

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The anti-inflammatory and antinociceptive activities of Triphala recipe were studied in animal models. Triphala recipe (4 mg/ear) significantly exhibited an inhibitory effect on the ear edema formation induced by ethyl phenylpropiolateinduced, but not on the arachidonic acid -induced ear edema in rats. Furthermore, Triphala recipe at the doses of 300, 600 and 1,200 mg/kg significantly reduced carrageenan-induced hind paw edema. Next, the anti-inflammatory action in chronic inflammation was measured using the cotton pellet-induced granuloma formation assay in rats. Triphala recipe (1,200 mg/kg) reduced neither transudative weight nor granuloma formation. It also did not affect on body weight gain and thymus weight indicating that Triphala recipe does not have a steroid-like effect. In antinociceptive study, Triphala recipe (300, 600, 1,200 mg/kg), elicited significant inhibitory effect on both phases, especially in late phase, of the formalin test in mice suggesting that the antinociceptive action of Triphala recipe may be via both peripheral and at least partly centrally acting.

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Section: Introductionmentioning

confidence: 99%

Evaluation of anti-inflammatory and antinociceptive activity of Triphala recipe

Sireeratawong¹,

Jaijoy²,

Soonthornchareonnon³

2013

Afr. J. Trad. Compl. Alt. Med.

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“…9 In another animal study, Triphala administration was found to be effective in decreasing weight as well as inhibiting elevation of LDL, VLDL and blood glucose levels. It also increased the HDL levels 8 and protecting liver function. 10 It also decreased lipid peroxidation 11 which is a major factor in the progression of atherosclerosis.…”

Section: Resultsmentioning

confidence: 86%

Efficacy and Safety Study of Triphala in Patients of Dyslipidemia: A Pilot Project

Kuchewar¹

2017

Int. J. Res. Ayurveda Pharm.

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Dyslipidemia has been found to be one of the most important contributing factors of coronary artery disease. The prevalence of dyslipidemia is very high in India, which requires urgent intervention strategies to prevent and manage this important cardiovascular risk factor. This study was aimed to explore the efficacy of Triphala churna on Dyslipidemia. It was Randomized, clinical study. Total 15 patients were selected from Kayachikitsa & Geriatric OPD as well as from peripheral diagnostic camps. Triphala churna 5 gm twice a day was given for continuous 30 days. Body weight and lipid profile were assessed before and after treatment. Safety was assessed by the incidence of adverse events. Significant changes were found in lipid levels and body weight. There was improvement in bowel habits. No any adverse effect was found. It can be concluded that Triphala churna might be a preferable medicine to control lipids.

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“…Also were used for treatment of disorders related to respiratory tract, hepatic, and gastrointestinal also was associated with hypolipidemic effect. Antioxidant and reactive oxygen species scavenging properties in Triphala have been observed [31], [32]. The essential oils of Rhynchosia minima, Cistanche phelypaea and Striga hermonthica exhibited antioxidant activity [9], [33], [34].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant potential of some Sudanese medicinal plants used in traditional medicine

EL-Kamali

Hamed²

2015

Int. J. Sci. World

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In the present work methanolic and water extracts of 19 medicinal plants, commonly used in Sudanese folk medicines against gastrointestinal tract, infectious diseases were investigated for their antioxidant activity. Antioxidant assays were carried out by using different in vitro models such as DPPH (2, 2-diphenyl-1picrylhydrazyl) radical scavenging and Iron chelating activity. Methanolic and water extracts of Punica granatum showed the highest total antioxidant activity of 71±0.03 and 73±0.01 respectively. The antioxidant activities of water extracts were poor when compared to the methanol extract. The iron chelating power of methanol and aqueous extracts of Commiphora myrrha 58±0.01 and Azadirachta indica 57±0.20 respectively.

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Hypolipidemic Effect of Triphala in Experimentally Induced Hypercholesteremic Rats

Cited by 73 publications

References 17 publications

Evaluation of anti-inflammatory and antinociceptive activity of Triphala recipe

Evaluation of anti-inflammatory and antinociceptive activity of Triphala recipe

Efficacy and Safety Study of Triphala in Patients of Dyslipidemia: A Pilot Project

Antioxidant potential of some Sudanese medicinal plants used in traditional medicine

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