Hypolipidemic, Hypoglycemic and Anti-oxidant Activities of Flower Extracts of <i>Allamanda Violacea</i> A. DC (Apocynaceae)

Abstract

Purpose: To investigate the anti-dyslipidemic, anti-oxidant and anti-diabetic activities of the aqueous extract and solvent fractions of A. violacea flowers. Methods:The aqueous extract was fractionated into petroleum ether, ether, chloroform, chloroformmethanol (4:1) and chloroform-methanol (3:2) 24, 23, 23 and 22 %, and 24, 22, 23 and 19 %, respectively. In rats fed with high fat diet (HFD), ether and chloroform fractions lowered Tc, Tg and, Pl by 26, 25 and 26 %,and 18, 19 and 20 %, respectively