Hyponatremia and psychotropics

Sahoo, Swapnajeet

doi:10.4103/2348-9995.195604

Cited by 20 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Euvolemic hyponatremia may also be caused by various drugs (antidepressants, opioids and antipsychotics [21], thiazides, some anti-cancer drugs, nonsteroidal anti-inflammatory drugs) [22], and recreational drugs (ecstasy) -or excessive fluid use during transurethral resection (TUR) syndrome, colonoscopy or cardiac catheterization intervention [9], and cerebral salt wasting [23].…”

Section: Hypovolemic Hypotonic Hyponatremiamentioning

confidence: 99%

Etiology, Clinical Approach, and Therapeutic Consequences of Hyponatremia

Spasovski,

Lameire

2023

Preprint

View full text Add to dashboard Cite

The perturbation in water balance rather than any change in salt content is the main cause of hyponatremia, the most frequent electrolyte abnormality defined as serum sodium concentration <135 mEq/L. Hyponatremia may be divided as mild (Na>120 mEq/L) or severe (Na<120 mEq/L) hyponatremia, most frequently observed in elderly ICU hospitalized patients. Based on tonicity hyponatremia may be hypotonic (decreased concentration of solute), isotonic, and hypertonic (falsely low sodium). According to the volume of the extracellular fluid (ECF) hyponatremia is further divided as hypovolemic, euvolemic, or hypervolemic hyponatremia. Finally, hyponatremia may develop rapidly as acute (<48 h) with usually severe symptoms, or slowly as chronic hyponatremia, being usually asymptomatic or with mild symptoms. Patient’s medical history and clinical symptoms and signs could point to a certain diagnostic direction. Acute severe hyponatremia is presented with headaches, vomiting, nausea, fatigue, impaired cognition, gait with increased falls symptoms etc., while the severe symptomatology due to hyponatremic encephalopathy is presented as confusion, agitation, seizures, or even coma and death. Nevertheless, an urgent evaluation of the volume and neurological status is essential for prevention of neurological damages. The treatment of hyponatremia should of course be based on the underlying cause, the duration and degree of hyponatremia, the observed symptoms, and volume status of patient.

show abstract

Section: Hypovolemic Hypotonic Hyponatremiamentioning

confidence: 99%

Etiology, Clinical Approach, and Therapeutic Consequences of Hyponatremia

Spasovski,

Lameire

2023

Preprint

View full text Add to dashboard Cite

show abstract

Forecasting hyponatremia in hospitalized patients using multilayer perceptron and multivariate linear regression techniques

Theerthagiri

2021

Concurrency and Computation

View full text Add to dashboard Cite

The percentage of patients hospitalized due to hyponatremia is getting higher. Hyponatremia is the deficiency of sodium electrolyte in the human serum. This deficiency might indulge adverse effects and also be associated with longer hospital stay or mortality if it was not actively treated and managed. This work predicts the futuristic sodium levels of patients based on their history of health problems using a multilayer perceptron (MLP) and multivariate linear regression (MLR) algorithm. This work analyzes the patient's age, information about other diseases such as diabetes, pneumonia, liver disease, malignancy, pulmonary, sepsis, SIADH, and a sodium level of the patient during admission to the hospital. The results of the proposed MLP algorithm is compared with the MLR algorithm-based results. The MLP prediction results generate 23%-72% of higher prediction results than the MLR algorithm. Thus, the proposed MLP algorithm has produced 57.1% of the reduced mean squared error rate than the MLR results on predicting future sodium ranges of patients. Further, the proposed MLP algorithm produces 27%-50% of the higher prediction precision rate. Therefore, the MLP algorithm can be used for forecasting patient's hyponatremia.

show abstract

Psychosis and Physical Comorbidity

Seeman

2019

Mental Health and Illness of Women

View full text Add to dashboard Cite

Hyponatremia and psychotropics

Cited by 20 publications

References 8 publications

Etiology, Clinical Approach, and Therapeutic Consequences of Hyponatremia

Etiology, Clinical Approach, and Therapeutic Consequences of Hyponatremia

Forecasting hyponatremia in hospitalized patients using multilayer perceptron and multivariate linear regression techniques

Psychosis and Physical Comorbidity

Contact Info

Product

Resources

About