Hyponatremia as a First Sign of Small Cell Lung Cancer: A Case Report

Severe hyponatremia as the presenting manifestation of primary empty sella syndrome

“…In addition, hyponatremia can be the first presentation of several occult diseases such as lung cancer, cryptococcal, and tuberculosis meningitis. 2 , 3 , 4 The main pathogenesis of hyponatremia is excess water intake or inability of the kidney to excrete water, usually because of elevated serum antidiuretic hormone (ADH) levels. 5 Normally, ADH secretion is stimulated by high plasma osmolality and low effective circulating volume.…”