Hypophonia in Parkinson’s disease

Liotti, Mario; Ramig, Lorraine O.; Vogel, Deanie; New, Pamela; Cook, C. I.; Ingham, Roger J.; Ingham, Janis C.; Fox, Peter T.

doi:10.1212/wnl.60.3.432

Cited by 185 publications

(147 citation statements)

References 33 publications

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“…It is interesting to relate our observations of force-related BG activation to previous studies indicating a relation between activity in the BG and the speed of arm movement (Taniwaki et al, 2003;Turner et al, 2003a,b) and control of speech volume (Liotti et al, 2003). Taken with results from non-human primate studies using single cell recording (Georgopoulos et al, 1983;Turner and Anderson, 1997), neuronal inactivation (Alamy et al, 1995;Inase et al, 1996;Mink and Thach, 1991) and electrical stimulation (Horak and Anderson, 1984), this supports the hypothesis that the BG contribute to the control of movement scale.…”

Section: Discussionsupporting

confidence: 87%

Force related activations in rhythmic sequence production

et al. 2005

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Section: Discussionsupporting

confidence: 87%

Force related activations in rhythmic sequence production

et al. 2005

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“…Moreover, activity-dependent changes observed in both motor and association white matter fiber tracts support the notion that both feedforward and feedback speech production networks can be strengthened through an intensive voice and speech treatment protocol in children with CP. Our findings are in line with previous studies showing positive voice and speech outcomes and associated functional neural activity in adults with Parkinson disease following LSVT LOUD [64,65] , indicating that, even though neurological etiologies are different, activity-dependent neuroplastic changes can be achieved.…”

Section: Treatment-dependent Neuroplasticitysupporting

confidence: 93%

“…That's how it feels when you are using healthy vocal loudness.) and align with previous findings from PET imaging studies following LSVT LOUD in Parkinson patients [64,65] and can be interpreted in the context of enhancement of the feedback system [43] . The trend for a fast-phase change in the right PLIC may be related to the nature of external and internal somatosensory feedback used to modulate adjustments to laryngeal function (pitch and loudness) along with changes in mouth opening (loudness) as well as functional phrase repetitions that encourage articulatory practice involving the tongue.…”

Section: Behavioral Outcomessupporting

confidence: 88%

Changes in White Matter Integrity following Intensive Voice Treatment (LSVT LOUD®) in Children with Cerebral Palsy and Motor Speech Disorders

Reed¹,

Cummine²,

Bakhtiari³

et al. 2017

Dev Neurosci

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Preliminary evidence suggests that intensive voice and speech treatment based on activity-dependent neuroplasticity principles holds promise for affecting positive change in children with cerebral palsy (CP) and motor speech disorders. Diffusion tensor imaging (DTI) allows researchers to make inferences about the integrity of white matter tracks and provides a sensitive measure of neuroplasticity. Previous treatment studies looking at the effects of training on white matter integrity have shown positive results, but these studies have been limited to gross motor function. Eight children with motor speech disorders and CP (3 females; age 8-16 years) and an age- and sex-matched group of typically developing (TD) children participated. Each child with CP completed a full dose of LSVT LOUD® and a 12-week maintenance program. Participants attended 3 recording sessions: before and after treatment, and after the maintenance period. TD children were tested at the same 3 time points. Recording sessions for both groups of children included measures of white matter integrity using DTI and acoustic measures of voice and speech. Fractional anisotropy (FA) was measured for 2 motor tracts and 5 association tracts. In children with CP, we observed an increase in FA in several motor and association tracts immediately following treatment and 12 weeks after treatment. Acoustic data on untrained tasks were correlated with changes in FA detected immediately following treatment and after the 12-week maintenance program. These findings suggest that long-term practice of skills attained during the treatment phase enhances white matter tract integrity in speech production networks.

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“…This technique provides intensive practice to increase speech effort and thus improve loudness and articulatory function. Recent studies have documented the effect of LSVT on respiration [109] , tongue function [110] , and brain activity as measured using PET [111] . LSVT has been compared with other treatment approaches such as those that focus exclusively on respiratory function [112] .…”

Section: Management Assessment: Validation Of Techniquesmentioning

confidence: 99%

The Degenerative Dysarthrias: A Window into Critical Clinical and Research Issues

Yorkston¹

2007

Folia Phoniatr Logop

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Although diversity of symptoms and urgency of needs pose many challenges, management of the degenerative dysarthrias is a crucial aspect of clinical practice. The purpose of this article is to review current research literature on selected degenerative dysarthrias including those associated with Parkinson’s disease, multiple sclerosis, and amyotrophic lateral sclerosis. These dysarthrias are prevalent yet represent distinct patterns of underlying neuropathology, symptoms, age of onset, and rate of progression. Literature searches including the period 1997–2006 yielded 148 different studies reporting data on communication issues related to dysarthria. By far the largest category of studies was that which provided a basic description of speech production including the neurophysiologic, acoustic, or perceptual properties of dysarthria. Other categories included management (assessment and treatment) and the psychosocial consequences of dysarthria. While the topic of management of degenerative dysarthria is a focused one, it provides a window into many issues critical to the field of communication disorders including fundamental properties of speech production, development of evidence-based treatment techniques, the staging of these techniques into an effective management sequence, and the psychosocial consequences of communication disorders along with techniques to maintain communicative participation in the face of degenerative conditions.

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Hypophonia in Parkinson’s disease

Cited by 185 publications

References 33 publications

Force related activations in rhythmic sequence production

Force related activations in rhythmic sequence production

Changes in White Matter Integrity following Intensive Voice Treatment (LSVT LOUD®) in Children with Cerebral Palsy and Motor Speech Disorders

The Degenerative Dysarthrias: A Window into Critical Clinical and Research Issues

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