Hypopituitarism

Rosenquist, Klara J.; Kaiser, Ursula B.

doi:10.1002/9781118559406.ch12

Pituitary Disorders 2013

DOI: 10.1002/9781118559406.ch12

|View full text |Cite

Hypopituitarism

Klara J. Rosenquist

Ursula B. Kaiser

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2019

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

A 24-Year-Old Male with Gigantism, Growth Hormone Deficiency, Suspected Clivus Chordoma, Primary Hypothyroidism, Hypogonadism and Pancytopenia

Arsana¹,

Pramudianti²

2019

Indonesian J. Clin. Pathol. Med. Lab.

View full text Add to dashboard Cite

Preeliminary : Pituitary gigantism is a condition caused by the excessive secretion of growth hormone (GH). Growth Hormone is also the most common pituitary hormone deficient in pituitary disease. Chordoma is a bone primary tumor that grows slowly and rarely found. Hypothyroidism is a pathological condition due to thyroid hormone deficiency. Symptoms of hypogonadism is non-specific including libido disorders, erectile dysfunction and decreased muscle mass and no hair growth in the head or body. Case : A 24-year-old man came with a knee-jerk complaint. Physical examination obtained increased growth of statural and body parts as well as loss of body hair. Laboratory investigation revealed pancytopenia, increased prolactin; decreased GH, IGF-1 and testosterone; increased TSH, decreased FT3 and FT4. Head MRI demonstrated the presence of mass in the clivus.Discussion : In this case, the patient presents with clinical gigantism. However, laboratory examination shows decreased GH and IGF-1 which may be due to the suppressive effect of mass on the clivus bone to the pituitary. The suspicion of hypothyroid found alone or due to mass in the clivus bone still requires further examination. Hypogonadism can result from supression on the pituitary. Pancytopenia can be caused by deficiency of GH or from hypothyroidism.Conclusion : Gigantism may occurred with deficiency GH and IGF-1 due to suppressed pituitary caused by chordoma.

show abstract

A 24-Year-Old Male with Gigantism, Growth Hormone Deficiency, Suspected Clivus Chordoma, Primary Hypothyroidism, Hypogonadism and Pancytopenia

Arsana¹,

Pramudianti²

2019

Indonesian J. Clin. Pathol. Med. Lab.

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Hypopituitarism

Cited by 1 publication

References 34 publications

A 24-Year-Old Male with Gigantism, Growth Hormone Deficiency, Suspected Clivus Chordoma, Primary Hypothyroidism, Hypogonadism and Pancytopenia

A 24-Year-Old Male with Gigantism, Growth Hormone Deficiency, Suspected Clivus Chordoma, Primary Hypothyroidism, Hypogonadism and Pancytopenia

Contact Info

Product

Resources

About