Hypoplasia of the Mandible

Llewellyn, John S.; Biggs, Alfred D.

doi:10.1001/archpedi.1943.02010150088008

Cited by 23 publications

(5 citation statements)

References 4 publications

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“…Apart from their occurrence in the Treacher Collins syndrome, these features may be present alone, comprising the Pierre Robin syndrome. As described by Lenstrup (1925), Ely and Farber (1930), Davis and Dunn (1933), Robin (1934) and Lapage (1937), the condition shows a remarkable tendency to spontaneous improvement; this, and the fact that the symphysis menti is nearly vertical and the angle of the mandible nearly a right angle (Walker, 1956), have diverted attention from the purely teratogenic theory of origin to that expressed by Llewellyn and Biggs (1943), viz., that the micrognathia is purely a mechanical effect produced by the pressure of the chin against the sternum in the vertex position of the foetus; these authors went even further: they claimed that the frequent complication of cleft palate may be the result of the tongue being pushed back into the mouth and preventing the fusion of the palatal processes. Mandibular Dysostosis.…”

mentioning

confidence: 98%

The First Arch Syndrome

McKenzie¹

1958

Archives of Disease in Childhood

152

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confidence: 98%

The First Arch Syndrome

McKenzie¹

1958

Archives of Disease in Childhood

152

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“…Transferred to K. L. B., on Xovember 14th of the same year, in a bad condition. The diagnosis was confirmed, a. o. with positive guinea-pig test in C. 8. F. which also contained approximately 300 Icukocytes/nini~.…”

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confidence: 78%

“…Some authors claim t o have stimulated the development of the lower jaw through constant liuliing with the aid of some headgear (4) or by a special traction apparatus (5); otliers, referring to successful experiments, recommend a meclianical dcrica on the bottle that forces the infant to push its chin forward in order to suck (6). A brace behind the anguli mandibulae to lift the lower j a w forward (3, 7 , 8) has often been tried. In a few cases trac31ieotomy has even been performed (9).…”

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confidence: 99%

Diplomycin Treatment in a Case of Tuberculous Meningitis

1950

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Diplomycin, a new antibiotic, and its clinical applicability l i a~~ bwii studied in Germany arid Denmark during the past two ycars. Tlie nvtivc: substance comes from a special diploc,occus strain from which it derives its name. Morphologically, this bacterium is an oval or lancet-s11a~pcct coccus, growing in pairs or in short t~.hai~is. Biologically, it mostly rcsernbles Streptococcus lacticus. I t was isolated by NOSTER (1) in 1945. IIc accidentally found and unknown gram-positive Diplococcus growiiig iii :L culture from a patient's sput,um. Bactwiurn-free filtrat,es of a 1 per cc,nt glucose broth, where this Diplococcus had grown, had a hacte,riost,;i,tic: a s well as bactericide effect ( 1 , 2, 3, 4). NOSTER considered this effect t,o be connected wit'li the bacterial secretion product's. I t nourictid b0t.h oil gram-positive and gram-ncgat,ive strains, a. o. 011 tubcrcle bacilli.Diplomyciri is produced in Gwniany aiid Denmark for cliniral usti. The filtrates differ for local application autl for intravenous adniiiiist,rntion. So far, no preparatioii has boen obta,ined that can be inj(:c:t,td intramuscularly.The toxicity of diplomycin is vory slight. No cliangcs 1i:tve bwn ohscrved in the blood, nor lixs any damage been not,td in the ltidiioys or in the nervous system as, for insta,nw, in strcptomyciii tlierapy, alt,ltoiigli diploniyciii was administered daily to paLtirnts for several months.Diplomycin tias it coiispicuous smell of broth. Irrimcdiately a,ft,er an inject'ion, most of the patients were subjected to a, flusliitig of the fncc : i t i d heart palpitat,ions. They also comphined of a marknd heat sctis;itioii iti the body arid a 1ic:adaclie. However, these symptoms clisappea.reci aftcr a few minutes. The heada.clie may oce.asionally last for one or two hours. Also a short rise in the t.e.tnpera,ture, sornetimcs aooonipanie.d by a chill, has been noticed, some hours a.fter the injection. According t o tho experience collected, one daily injection of diplomycin seems t o be sufficient.Our attention was drawn t o this remedy by the statement that diplomycin has an effect on tubercle bacilli. Thus, KLIYANEK (qiiot,ed by NOSTER) ( 5 ) found diplomycin useful in the treatment of piilnioliary

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“…-nasion, a point on the suture between the frontal and nasal bones. 6. S-sella turcica; the center of the sella turcica is determined by inspection.…”

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confidence: 99%

GROWTH OF MANDIBLE IN INFANTS WITH MICROGNATHIA<subtitle>Clinical Implications</subtitle>

Pruzansky¹

1954

Arch Pediatr Adolesc Med

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Hypoplasia of the Mandible

Cited by 23 publications

References 4 publications

The First Arch Syndrome

The First Arch Syndrome

Diplomycin Treatment in a Case of Tuberculous Meningitis

GROWTH OF MANDIBLE IN INFANTS WITH MICROGNATHIA<subtitle>Clinical Implications</subtitle>

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