Hypoplastic kidney with hyperplastic mesonephric remnants as a cause of unilateral non-functioning kidney in an adult male

Congenital Unilateral Hypoplasia of Kidney with Mesonephric Remnants in the Ureter: A Case Report

“…[ 1 ] Nephrogenesis requires perfect coordination of all events and also the failure of regression of primary structure may hamper the development of secondary ones and may also lead to the persistence of remnants. [ 4 ] MRs have been reported in the urogenital organs of both males and females. In males, it includes the urethra, prostate, renal pelvis, spermatic cord, and vas deferens, and in females, MRs are seen in the cervix, vagina, adnexa, and uterine corpus.…”

“…In males, it includes the urethra, prostate, renal pelvis, spermatic cord, and vas deferens, and in females, MRs are seen in the cervix, vagina, adnexa, and uterine corpus. [ 4 ] Usually, the organs with the mesonephric remnants are well developed and functional; however, occasionally they may be associated with other developmental anomalies such as renal hypoplasia. [ 4 ] The MND tubulocystic structures along with renal agenesis or MCDK arise from the ureteric bud structures and present as a ureterocele with or without a blind-ending ureter-like structure.…”

“…[ 4 ] Usually, the organs with the mesonephric remnants are well developed and functional; however, occasionally they may be associated with other developmental anomalies such as renal hypoplasia. [ 4 ] The MND tubulocystic structures along with renal agenesis or MCDK arise from the ureteric bud structures and present as a ureterocele with or without a blind-ending ureter-like structure. [ 1 ] In the present case, the patient presented with a hypoplastic kidney along with a small blind ending ureter-like structure grossly.…”

“…Wang et al . [ 4 ] also reported mesonephric remnants in the renal parenchyma that resembled epididymis, vas deferens, and seminal vesicles.…”

“…[ 3 ] The mesonephric remnants may proliferate and may become hyperplastic and also occasionally may result in malignant transformation, leading to mesonephric carcinoma. [ 4 ] Although cases of mesonephric remnants (MR) are reported in the pelvis including the genitourinary tract in both the males and females, only a few cases of mesonephric remnants have been reported in the renal parenchyma[ 3 4 5 6 ] in the literature.…”