Hypothalamic Tuberculoma Associated with Secondary Panhypopituitarism

Flannery, Michael T.; Pattani, Sita; Wallach, Paul M.; Warner, Elizabeth A.

doi:10.1097/00000441-199308000-00007

Cited by 26 publications

(12 citation statements)

References 12 publications

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“…(Flannery et al, 1993;Bell and Sachs, 1988). Tuberculoma is encountered in 15 to 30% cases of CNS tuberculosis and is mostly hemispheric (Arvind et al, 1993;Mitchell et al, 1994).…”

Section: Discussionmentioning

confidence: 99%

CNS tuberculoma mimicking brain metastasis

Gautam

Shrivastava²,

Khare³

et al. 2014

IJM

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A 32 year old male patient, a follow up case of carcinoma tongue post radiotherapy, presented with history of non-healing ulcer on lateral aspect of neck since 2 years and recurrent episodes of seizures for about 13 months duration. Neuroimaging was suggestive of metastasis in brain and patient was referred to us for biopsy of the lesion. Detailed clinical and radiological work up followed by neurosurgical intervention established the diagnosis of neurotuberculosis. In a patient with primary systemic malignanacy with suspected central nervous system metastasis, brain tuberculoma should always be kept as a differential diagnosis. Keywords: Brain Metastasis, Carcinoma Tongue, Tuberculoma.

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“…(Flannery et al, 1993;Bell and Sachs, 1988). Tuberculoma is encountered in 15 to 30% cases of CNS tuberculosis and is mostly hemispheric (Arvind et al, 1993;Mitchell et al, 1994).…”

Section: Discussionmentioning

confidence: 99%

CNS tuberculoma mimicking brain metastasis

Gautam

Shrivastava²,

Khare³

et al. 2014

IJM

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“…However, tuberculoma due to solid granulomatous lesion can present as focal neurological signs. Hypothalamic tuberculoma causing secondary panhypopituitary dysfunction had been reported in a man 6. The combination of isolated hypogonadotropic hypogonadism with anosmia is known as Kallmann syndrome.…”

Section: Discussionmentioning

confidence: 99%

An unusual cause of isolated secondary ovarian failure due to cerebral toxoplasmosis in an African woman with AIDS

Yoganathan

Sadiq

Yoganathan³

2017

BMJ Case Reports

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Primary ovarian failure is common. However, isolated secondary ovarian failure due to gonadotrophin deficiency is rare. A few cases of isolated gonadotrophin deficiency, due to congenital cerebral toxoplasmosis, have been described in children. We report the case of a 34-year-old African woman positive for HIV, who developed secondary amenorrhoea following the successful treatment of cerebral toxoplasmosis. Investigations revealed that she developed an isolated gonadotrophin deficiency due to pituitary lesion. The rest of the pituitary function dynamic tests were normal.

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“…In the present case, MRIfindings matched well with the previous reports. However, tuberculomas showing a wide variety of signal intensities have also been reported (9,12,13), presumably reflecting different stages of tuberculoma. Additionally, malignant glioma, brain abscess, cysticercus granuloma, metastatic cancer or lymphomaresembles tuberculoma on the radiological study (6).…”

Section: Discussionmentioning

confidence: 99%

Solitary Pontine Tuberculoma.

et al. 2002

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A 66-year-old man, with a history of pulmonary tuberculosis 40 years before admission, complained of headache and dysarthria that lasted for 2 weeks and was followed by diplopia. MRIrevealed an isolated nodular lesion in the pons with a marked enhancement mimicking brain tumor and other diseases. Antituberculous drugs were started under the presumptive diagnosis of tuberculoma. The lesion was completely resolved after 9 months of treatment and thus, the final diagnosis was confirmed. Anempiric administration of antituberculous drug may be an important and non-invasive diagnostic tool as well as a treatment in such cases. (Internal Medicine 41: 738-742, 2002)

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Hypothalamic Tuberculoma Associated with Secondary Panhypopituitarism

Cited by 26 publications

References 12 publications

CNS tuberculoma mimicking brain metastasis

CNS tuberculoma mimicking brain metastasis

An unusual cause of isolated secondary ovarian failure due to cerebral toxoplasmosis in an African woman with AIDS

Solitary Pontine Tuberculoma.

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