Hypothermia-Related Acute Pancreatitis

Kh, Lin; Ofori, Emmanuel; Lin, Aung Naing; Lin, Sithu; Lin, Thinzar; Rasheed, Ameer; Vasudevan, Viswanath; Reddy, Madhavi

doi:10.1159/000489296

Cited by 4 publications

(3 citation statements)

References 12 publications

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“…Mildly elevated serum amylase without clinical evidence of pancreatitis is common in the state of hypothermia, being present in 50 to 65% of patients [1,[17][18][19], and as the body temperature decreases, the serum amylase levels rise [18]. Due to the absence of epigastric abdominal pain in this patient, acute pancreatic inflammation has not been ini-tially diagnosed.…”

Section: Discussionmentioning

confidence: 80%

Multy-system complications of accidental hypothermia: A case report

et al. 2020

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Introduction. Accidental hypothermia is an unintentional fall in core temperature to less than 35?C and it occurs when the body?s heat loss exceeds its heat production. The elderly population is particularly susceptible due to reduced adaptability to low temperatures and various comorbidities, which may be predisposing factors. Case Report. A 65-year-old Caucasian female was admitted to the hospital due to hypothermia (< 34?C), severe hypoglycemia (0.7 mmol/L), metabolic acidosis (6.970), elevated urea (42.4 mmol/L) and creatinine (686 ?mol/L). The initial examination revealed shivering, dysarthria and general exhaustion. Hyperamylasemia (241 U/L) and hyperlipasemia (1920 U/L) were found on the second day after admission. Contrast enhanced computed tomography showed a focal asymmetric enlargement of the pancreatic head and body. Furthermore, a splenic infarction was also noticed. The complexity of human thermoregulatory mechanisms indicates the importance of precipitating factors in the development of hypothermia. Our patient presented with several precipitating factors such as age, sex, urinary tract infection, diabetes, and metformin-induced severe hypoglycemia. Conclusion. Based on the presented case and the relevant literature, it can be concluded that the clinical picture of hypothermia may be extremely complex. Knowledge of all the mechanisms involved in multi-organ failure due to hypothermia is of utmost importance, in order to conduct adequate and timely targeted diagnosis and apply appropriate treatment.

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Section: Discussionmentioning

confidence: 80%

Multy-system complications of accidental hypothermia: A case report

et al. 2020

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“…It has been shown that internal rewarming strategies do not provide any extra benefits, and complications related to coagulation and bleeding can result [12]. Uncomplicated mild to moderate acute pancreatitis in hypothermic patients is conservatively managed with efforts to normalize temperature, aggressive fluid resuscitation, and antibiotic therapy [13]. However, moderately severe or severe acute pancreatitis is managed in the ICU with consideration given to surgical therapy based on the complications.…”

Section: Discussionmentioning

confidence: 99%

Acute Pancreatitis Associated With Hypothermia: An Uncommon Presentation

Khan

Yousaf

Jamil

et al. 2020

Cureus

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Hypothermia is not known as a common cause of acute pancreatitis, although there have been previously reported cases. Herein, we describe a 55-year-old man who presented with acute pancreatitis preceded by hypothermia in the absence of the more traditional causative factors, such as gallstones or alcohol consumption. On arrival to the emergency department, he was found to have a temperature of 84.3°F, consistent with moderate hypothermia, a blood pressure of 84/50 mmHg, and a heart rate of 60 bpm. Serum lipase and amylase levels were 2,225 and 980 U/L, respectively. A CT scan of the abdomen with intravenous (IV) contrast revealed peripancreatic fat stranding, consistent with the diagnosis. No evidence of gallstones or common bile duct dilatation was found. He had also developed acute kidney injury and lactic acidosis consistent with end-organ damage. After appropriate triage, he was admitted to the intensive care unit and supportively managed. An external rewarming strategy with IV fluids and antibiotics resulted in improvement in clinical status. Hypothermia can cause subtle changes in the microvasculature and production of free radicals, which can result in acute pancreatitis. It is important to determine the etiology so that appropriate treatment can be instituted with better outcomes.

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“…Peneliti mendapatkan hasil bahwa riwayat konsumsi alkohol tidak punya hubungan yang signifikan dengan stabilitas thermoregulasi, hal ini sejalan dengan penelitian yang dilakukan Patrizio bahwa pada pasien hipotermia, terjadi peningkatan keparahan penyakit tidak terkait dengan suhu awal, jenis kelamin, alkohol atau trauma (Petrone P et al 2020). Namun penelitian tersebut tidak sejalan dengan Kyawzaw Lin, yaitu ada beberapa kasus yang diindikasi hipotermia namun sementara akibat penyalah gunaan alkohol kronis (Lin, K et al, 2018). Minuman beralkohol bereaksi pada tubuh manusia dengan melebarkan pembuluh darah sehingga panas tubuh dapat didistribusikan dengan cepat, hal ini dapat memberikan sensasi hangat pada tubuh manusia.…”

Section: Tingkat Efektifitas Blanket Warmer Terhadap Stabilitas Therm...unclassified

Efek Pemberian Blanket Warmer Terhadap Thermoregulasi Pasien Perioperatif Transurethral Resection of the Prostate (Turp)

Firmansyah,

Nursanti,

Irawati

et al. 2022

Jurnal Perawat Indonesia

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Perioperatively in BPH patients who underwent TURP action caused thermoregulation disturbances which resulted in a decrease in temperature (hypothermia). This can occur due to exposure to environmental temperatures that are too extreme and the effects of anesthetic drugs during intraoperatively which can cause vasodilation of blood vessels and blocked sympathetic nerves so that they dominate the performance of the parasympathetic nerves. The purpose of the study was to determine the effectiveness of the Blanket Warmer in perioperative TURP patients at the Central Surgical Installation of Tarakan Hospital, Jakarta. The design of this study used a quasi-experimental pretest-posttest with control group design. The research sample was 48 respondents of TURP perioperative patients. The sampling technique was accidental sampling, the statistical test used was Paired t test. The results of the univariate analysis showed that the highest age was 50 years, about 89%, a history of drug consumption 54.2%, and a history of alcohol consumption as much as 29.2%. Bivariate test analysis between the intervention group and the control group obtained a p value of 0.001 <0.05, which means that there is a significant difference in the two groups. The multivariate test obtained p value > 0.05, meaning that the variables of age, history of drug consumption and history of alcohol consumption did not have a significant effect on thermoregulation stability. That there is an effect of giving a Blanket Warmer on the stability of thermoregulation in perioperative TURP patients. Suggestions for further research that a blanet warmer can stabilize thermoregulation in perioperative TURP patients at the Central Surgical Installation of Tarakan Hospital Jakarta. Keywords: TURP, Blanket Warmer, Thermoregulation Stability

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Hypothermia-Related Acute Pancreatitis

Cited by 4 publications

References 12 publications

Multy-system complications of accidental hypothermia: A case report

Multy-system complications of accidental hypothermia: A case report

Acute Pancreatitis Associated With Hypothermia: An Uncommon Presentation

Efek Pemberian Blanket Warmer Terhadap Thermoregulasi Pasien Perioperatif Transurethral Resection of the Prostate (Turp)

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