Hypothesis: Chronic Benign Daily Headache is an Immune Disorder with a Viral Trigger

Vanast, Walter; Díaz‐Mitoma, Francisco; Tyrrell, D. L. J.

doi:10.1111/j.1526-4610.1987.hed2703138.x

Cited by 30 publications

(17 citation statements)

References 16 publications

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“…Abrupt transition of episodic migraine to chronic migraine also suggests similar possibilities. Vanast [18], in 1987, suggested autoimmune disorder with a persistent viral trigger for chronic benign daily headache (NDPH). Tissue specificity is a general feature of post-infectious immune-mediated conditions [4].…”

Section: Discussionmentioning

confidence: 99%

Post-infectious headache: a reactive headache?

et al. 2011

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Post-infectious disease syndrome includes both neurological and non-neurological disorders. However, headache as an isolated or a presenting complaint of post-infectious illness has not been well acknowledged in the literature. In this retrospective observation, patients having daily headache of more than 1 week and <4 weeks duration were included. We divided this group into patients having headache with preceding history of febrile illness in the recent past and patients without such history of febrile illness. We compared clinical features and therapeutic responses of various drugs between the groups. There were no significant differences in demographic features in these groups. However, associated neck pain, nausea, photophobia and meningeal signs were more prevalent in patients having history of preceding infection. A relatively lower proportion of subjects showed complete response to drugs at 3 months in post-infectious group. Good responses were noted to steroids in post-infectious group. In conclusion, a subset of patients with daily headache may be because of post-infectious pathology and treatment in the early stage may prevent it from becoming chronic. Large prospective studies are required to confirm these observations.

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Section: Discussionmentioning

confidence: 99%

Post-infectious headache: a reactive headache?

et al. 2011

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“…They do not have a previous history of migraine or TTH and there is no clear history of trauma [12••]. Epstein-Barr virus has been suggested as an etiology [13]. Its nature suggests it may be related to TTH or migraine headache, or it may represent a new type of previously unclassified headache [14].…”

Section: New Persistent Daily Headachementioning

confidence: 99%

Overview of tension-type headache

Schulman¹

2001

Current Science Inc

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Tension-type headache (TTH) is the most prevalent form of headache. Although it is not the most severe form of headache, it has a significant impact on society. In spite of this, little is known about its pathophysiology. Current International Headache Society classification has been called into question, and new classification approaches have been suggested. With reference to chronic TTH, the issue of analgesic rebound may confound the diagnosis. Transformed migraine and new persistent daily headaches are clarified and differentiated from chronic TTHs (CTTHs). The best documented abnormality found in TTHs is the presence of pericranial tenderness. It is generally believed that pain is initiated by a peripheral mechanism, most likely increased input from the myofascial nociceptors. In CTTH, there may be an impaired supraspinal modulation of the incoming stimuli. Whether there is an overlap in the continuum between TTH and migraine is controversial. Abortive and prophylactic treatments are discussed and wellness and adjunct therapy are also emphasized. Lastly, special attention is paid to the doctor-patient relationship in patients with difficult headaches.

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“…Comumente, tais pacientes podem lembrar-se claramente do início do evento, do dia ou hora em que a cefaléia começou 6,16 . A cefaléia é, em geral, mal definida, difusa, semelhante a pressão, ou, ocasionalmente, pulsátil, podendo combinar características da migrânea sem aura e da CTT 12,17 .…”

Section: Cefaléia Diária Persistente De Início Súbito (Cdpis)unclassified

Cefaléia crônica diária primária: características clínicas

Jevoux¹,

Filho²,

Souza³

1998

Arq. Neuro-Psiquiatr.

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RESUMO -Sob a designação de cefaléia crônica diária (CCD) primária agrupam-se diferentes tipos de cefaléia que se caracterizam por se manifestarem diária ou quase diariamente, por longos períodos de tempo. Esse conceito refere-se a temporalidade e não a um tipo específico de cefaléia. É importante conhecer a CCD primária e seus subtipos. Nesta revisão são criticamente abordadas as principais características clínicas da CCD e sua história natural, bem como alguns fatores possivelmente influenciadores na cronificação das cefaléias. PALAVRAS-CHAVE: cefaléia crônica diária, características clínicas. Primary chronic daily headache: clinical aspectsABSTRACT-Under the denomination primary chronic daily headache (CDH) there are different types of headache which present daily or near-daily, during long spells. This concept refers to temporality and not to a specific kind of headache. It is important to know the CDH and its natural history, as well as some factors that possibly turn it into chronic. They are critically reviewed here.KEY WORDS: chronic daily headache, clinical features.Tradicionalmente, qualquer cefaléia indefinida, de ocorrência diária ou quase diária, sem características migranosas nítidas e que poderia ou não ser provocada pelo estresse ou outros fatores psicológicos, era diagnosticada como cefaléia tensional [1][2][3] . Uma mudança nesse conceito somente se operou a partir do estudo de Mathew e col. 3, que introduziram o conceito de transformação da migrânea episódica (ME) em cefaléia crônica diária (CCD). A CCD foi mais bem reconhecida a partir de 1987, quando Mathew e col.4 publicaram informações adicionais com uma série maior de pacientes; baseados na história clínica, subdividiram a CCD em três submodalidades, ou seja, cefaléia do tipo tensional crônica (CTTC), cefaléia diária persitente de início súbito (CDPIS) e migrânea transformada (MT). Atualmente, a hemicrania contínua (HC) também faz parte do grupo de CCD primária; apesar disso não será discutida aqui.A CCD primária é de ocorrência frequente na prática cefaliátrica, apesar disso, o interesse pelo seu estudo é recente e são poucos os dados relativos à sua epidemiologia [5][6][7] . Estima-se que aproximadamente 35% a 40% dos pacientes avaliados nas mais importantes clínicas de cefaléia e 2% a 5% da população geral possam sofrer de CCD 4,8,9 . Sob a denominação de CCD primária agrupam-se diferentes tipos de cefaléias que se caracterizam por se manifestarem diária ou quase diariamente, por longos períodos de tempo 5 . Esse conceito refere-se a temporalidade e não a um tipo específico de cefaléia.

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Hypothesis: Chronic Benign Daily Headache is an Immune Disorder with a Viral Trigger

Cited by 30 publications

References 16 publications

Post-infectious headache: a reactive headache?

Post-infectious headache: a reactive headache?

Overview of tension-type headache

Cefaléia crônica diária primária: características clínicas

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