Hysterectomy versus hysterectomy plus oophorectomy for premenopausal women

Orozco, Leonardo J; Salazar, Arturo; Clarke, Jane; Tristán, Mario

doi:10.1002/14651858.cd005638.pub2

Cited by 11 publications

(3 citation statements)

References 23 publications

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“…The consensus is that increased energy intake, facilitated by widespread availability of energydense foods, has contributed, in concert with lower energy expenditure (e.g., reduced physical activity), to trends of positive energy balance (12). However, human diets are complex, and there are many specific dietary components that have, at various times, been implicated in T2D risk (Fig.…”

Section: Genetics and Dietmentioning

confidence: 99%

Exposing the exposures responsible for type 2 diabetes and obesity

Franks

McCarthy

2016

Science

226

159

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The rising prevalences of type 2 diabetes and obesity constitute major threats to human health globally. Powerful social and economic factors influence the distribution of these diseases among and within populations. These factors act on a substrate of individual predisposition derived from the composite effects of inherited DNA variation and a range of environmental exposures experienced throughout the life course. Although "Western" lifestyle represents a convenient catch-all culprit for such exposures, effective treatment and prevention will be informed by characterization of the most critical, causal environmental factors. In this Review, we examine how burgeoning understanding of the genetic basis of type 2 diabetes and obesity can highlight nongenetic exposures that drive development of these conditions.

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Section: Genetics and Dietmentioning

confidence: 99%

Exposing the exposures responsible for type 2 diabetes and obesity

Franks

McCarthy

2016

Science

226

159

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“…3,5 However, other authors continue to argue that, in the absence of a randomized clinical trial, the evidence against prophylactic oophorectomy derived from observational studies is not sufficient to change the practice. 7–10 …”

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confidence: 99%

Accelerated Accumulation of Multimorbidity After Bilateral Oophorectomy: A Population-Based Cohort Study

Rocca

Gazzuola-Rocca

Smith

et al. 2016

Mayo Clinic Proceedings

184

194

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Objective To study the association between bilateral oophorectomy and the rate of accumulation of multimorbidity. Patients and Methods In this historical cohort study, the Rochester Epidemiology Project records-linkage system was used to identify all premenopausal women who underwent bilateral oophorectomy before age 50 years between January 1, 1988, and December 31, 2007, in Olmsted County, Minnesota. Each woman was randomly matched to a referent woman born in the same year (± 1 year) who had not undergone bilateral oophorectomy. We studied the rate of accumulation of 18 common chronic conditions over a median of approximately 14 years of follow-up. Results Although women who underwent bilateral oophorectomy already had a higher multimorbidity burden at the time of oophorectomy, they also experienced a significantly increased risk of subsequent multimorbidity (P=.XX). After adjustments for 18 chronic conditions present at baseline, race/ethnicity, education, body mass index, smoking, age at baseline, and calendar year at baseline, women who underwent oophorectomy before age 46 years experienced an increased risk of depression, hyperlipidemia, cardiac arrhythmias, coronary artery disease, arthritis, asthma, chronic obstructive pulmonary disease, and osteoporosis. In addition, they experienced an accelerated rate of accumulation of the 18 chronic conditions considered together (hazard ratio, 1.22; 95% CI, 1.14–1.31; P<.001). Several of these associations were reduced in women who received estrogen therapy. Conclusion Bilateral oophorectomy is associated with a higher risk of multimorbidity, even after adjustment for conditions present at baseline and for several possible confounders. However, several of these associations were reduced in women who received estrogen therapy.

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“…Outrossim, a histerectomia pode envolver a remoção das tubas uterinas, a chamada salpingectomia; a remoção dos ovários (ooforectomia) e; a remoção dos ovários juntamente com as tubas uterinas, chamada de salpingooforectomia (OROZCO et al, 2008).…”

Section: Tipos De Histerectomiaunclassified