Loop Heat Pipes (LHP) are passive two-phase heat transfer devices, driven by capillary pumps that source energy for circulation of working fluid solely from the heat source. They have a proven track record in spacecraft thermal control as well as terrestrial applications. However, LHP may experience partial or complete wick dryout and thermal instabilities at rapid power-up steps or (and) rapid condenser cooling conditions change due to a rapid inflow of subcooled liquid from the condenser into the evaporator. Such cases do not have very wide coverage in literature and are usually presented as a little nuisance in testing of a particular LHP, for which some design workaround was found. Oftentimes suggested solutions trade performance or other design merits for robustness of operation. This article aims to review such case studies where phenomena similar to the described “cold shock” affected LHP performance. The aforementioned instabilities become even more pronounced in grid-like multievaporator LHP having multiple parallel connections between capillary pumps and compensation chambers, as heat and mass transfer between those elements becomes less definite and can eventually increase the heat leak into compensation chambers. Vulnerability of LHP with distributed network of evaporators to seemingly “safe” transient regimes fosters deeper analysis of the “cold shock” phenomenon. With comprehensive definition to the problem and a list of research questions, technical measures for getting rid of it in perspective LHP designs can be foreseen.