Hysterosalpingography is obsolete: hysterosalpingo-contrast foam sonography should be the alternative

Ramos, J.; Pellicer, Nuria; Sánchez, Manuel Fernández

doi:10.1016/j.rbmo.2022.05.021

Cited by 11 publications

(10 citation statements)

References 10 publications

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“…Infertility may be caused by a variety of contributing factors, originating from the female side, the male side, or, most frequently, both. One such factor may be fallopian tube mechanical obstruction and/or dysfunction, leading to tubal factor infertility, which is estimated to constitute a contributing factor in over 30% of cases with clinically apparent infertility [ 2 ]. At the same time, the presence of tubal obstruction may be the deciding factor between a first-line, simpler fertility treatment (for example, intrauterine insemination - IUI) and a more advanced one (in vitro fertilization or intracytoplasmic sperm injection - IVF/ICSI), not to mention the need for surgery [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Enhancing Fertility in the Same Cycle: A Case Report on Effects of Hysterosalpingo-Foam Sonography (HyFoSy) for a Couple With Mild Infertility

Ziogas,

Tsakos,

Tsagias

et al. 2024

Cureus

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Fertility issues are becoming increasingly prevalent, leading many couples to seek fertility treatment at specialized centers. Infertility is a diverse clinical condition, with multiple potential etiologic factors and variable severity in its manifestation. Regardless of the underlying factors and severity, routine fertility assessment rarely differs between cases, with an essential step being fallopian tube patency assessment. Hysterosalpingo-foam sonography (HyFoSy) is the latest available diagnostic technique to assess this parameter, offering robust results, with reduced intra-procedural pain and equipment requirements, in the convenience of the office setting. However, apart from its diagnostic value, HyFoSy has also demonstrated a therapeutic tubal flushing effect, that may be the decisive factor for couples with mild infertility to spontaneously conceive. In this report, we present the case of a couple with mild infertility, who managed to spontaneously conceive after a HyFoSy examination, and in fact within the same cycle.

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Section: Introductionmentioning

confidence: 99%

Enhancing Fertility in the Same Cycle: A Case Report on Effects of Hysterosalpingo-Foam Sonography (HyFoSy) for a Couple With Mild Infertility

Ziogas,

Tsakos,

Tsagias

et al. 2024

Cureus

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“…In 2007, Emanuel et al developed a new non-embryotoxic contrast medium (EXEM ® ) for performing hysterosalpingo-contrast sonography (HyCoSy) ( 4 ). This variant, called hysterosalpingo-foam sonography (HyFoSy), could improve diagnostic yield and efficacy compared with other ultrasonographic methods for tubal evaluation ( 5 ).…”

Section: Introductionmentioning

confidence: 99%

Sequential-contingent strategy for fallopian tube evaluation using hysterosalpingo foam sonography: a cost analysis

Armijo-Sánchez,

Santamaría-López,

Fernández-Sánchez

et al. 2024

Quant Imaging Med Surg

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Background Tubal pathology is the etiological factor in 20% of couples with female infertility. Historically, diagnostic evaluation of the fallopian tubes has been performed by means of hysterosalpingography (HSG). Hysterosonosalpingography with EXEM ® foam is a recent technique with supposedly comparable effectiveness to HSG, but with better tolerability for patients. Methods Tubal patency was assessed in patients who were candidates for intrauterine insemination (IUI) between January 2020 and July 2021. (I) Hysterosonosalpingography with EXEM ® foam. (II) If the patient had both tubes patent, IUI was proposed. In case of inconclusive or pathological results, HSG was performed. (III) If the HSG concludes tubal patency, IUI is proposed. On the other hand, if it results in tubal obstruction, in vitro fertilization (IVF) is proposed. Results Assessment of tubal patency by HSG showed concordance with previous Hysterosonosalpingography with EXEM ® foam results in 45.5% (n=15) of cases of unilateral obstruction and 66.7% (n=6) of cases of bilateral obstruction. When we compare the total cost of HSG (€54,899.46) with the sum of patients who only required Hysterosonosalpingography with EXEM ® foam together with those who underwent both tests (€45,575.96), it shows that the latter represents a cost benefit strategy (cost difference €9,323.50). Conclusions Our results suggest a benefit of €9,323.50 when performing the contingent sequential strategy, in case of pathological or inconclusive results, compared to performing a systematic HSG in all patients. Patients with an obstructive hysterosalpingogram with EXEM ® and a patent hysterosalpingogram will be the subgroup that will benefit the most, as IUI can be proposed instead of IVF. In addition, there is a benefit in terms of optimizing the medical procedure, hospital visits and speeding up the time to start assisted reproductive technology (ART).

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“…Infertility is defined as the inability to conceive within 12 months of regular intercourse without contraception, with up to 12% of couples worldwide being affected by it [ 1 ]. Fallopian tube pathology is a significant contributing factor, present in over 35% of infertility cases [ 2 ]. Given the prevalence of tubal factor infertility, tubal patency assessment is an essential procedure during every basic infertility workup.…”

Section: Introductionmentioning

confidence: 99%

Spontaneous Pregnancy in a Hysterosalpingo-Foam-Sonography (ΗyFoSy) Cycle: A Case Report and Review of the Available Literature

Lamari¹,

Xydias²,

Tsakos³

et al. 2023

Cureus

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Fallopian tube pathology is a very common cause of infertility for multiple couples worldwide. Tubal patency assessment is considered a crucial component of initial infertility evaluation with several evaluation tests available, such as hysterosalpingography (HSG), hysterosalpingo-contrast sonography (HyCoSy), and hysterosalpingo-foam sonography (HyFoSy), the latest tubal patency assessment, utilizing ultrasonography and a foam-based contrast agent. An additional side-benefit of these assessment tests is a fertilityenhancing effect, best studied with the application of HSG. In this report, we present a case of a 28-year-old woman with unexplained infertility who spontaneously conceived in the same menstrual cycle that the HyFoSy exam with ExEm ® foam (ExEm Foam Inc., Nashville, Tennessee, United States) was performed, without any additional fertility enhancement interventions.

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Hysterosalpingography is obsolete: hysterosalpingo-contrast foam sonography should be the alternative

Cited by 11 publications

References 10 publications

Enhancing Fertility in the Same Cycle: A Case Report on Effects of Hysterosalpingo-Foam Sonography (HyFoSy) for a Couple With Mild Infertility

Enhancing Fertility in the Same Cycle: A Case Report on Effects of Hysterosalpingo-Foam Sonography (HyFoSy) for a Couple With Mild Infertility

Sequential-contingent strategy for fallopian tube evaluation using hysterosalpingo foam sonography: a cost analysis

Spontaneous Pregnancy in a Hysterosalpingo-Foam-Sonography (ΗyFoSy) Cycle: A Case Report and Review of the Available Literature

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